Results 111 to 120 of about 150,481 (338)

Polarizing intestinal epithelial cells electrically through Ror2 [PDF]

open access: yes, 2014
© 2014.
Cao, Lin   +7 more
core   +3 more sources

Apical restriction of the planar cell polarity component VANGL in pancreatic ducts is required to maintain epithelial integrity

open access: yesbioRxiv, 2019
Cell polarity is essential for the architecture and function of numerous epithelial tissues. Here we show how planar cell polarity (PCP), so far studied principally in flat epithelia, is deployed during the morphogenesis of a tubular organ.
Lydie C. Flasse   +5 more
semanticscholar   +1 more source

A New Spin on Planar Cell Polarity [PDF]

open access: yesCell, 2010
The generation of planar cell polarity (PCP) and tissue shape during morphogenesis is tightly linked, but it is not clear how. Aigouy et al. (2010) now show in the developing Drosophila wing that PCP initially has a radial orientation that becomes realigned to the proximal-distal axis of organ shape by mechanical forces and cell rearrangements mediated
Olguin, Patricio, Mlodzik, Marek
openaire   +2 more sources

Photoswitchable Conductive Metal–Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
A conductive material where the conductivity can be modulated remotely by irradiation with light is presented. It is based on films of conductive metal–organic framework type Cu3(HHTP)2 with embedded photochromic molecules such as azobenzene, diarylethene, spiropyran, and hexaarylbiimidazole in the pores.
Yidong Liu   +5 more
wiley   +1 more source

Reciprocal action of Casein Kinase Iε on core planar polarity proteins regulates clustering and asymmetric localisation

open access: yeseLife, 2019
The conserved core planar polarity pathway is essential for coordinating polarised cell behaviours and the formation of polarised structures such as cilia and hairs.
Helen Strutt   +2 more
doaj   +1 more source

PLK-1 Regulation of Asymmetric Cell Division in the Early C. elegans Embryo

open access: yesFrontiers in Cell and Developmental Biology, 2021
PLK1 is a conserved mitotic kinase that is essential for the entry into and progression through mitosis. In addition to its canonical mitotic functions, recent studies have characterized a critical role for PLK-1 in regulating the polarization and ...
Amelia J. Kim, Erik E. Griffin
doaj   +1 more source

Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]

open access: yes, 2019
Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan   +4 more
core   +2 more sources

Cellular and molecular mechanisms underlying planar cell polarity pathway contributions to cancer malignancy.

open access: yesSeminars in Cell and Developmental Biology, 2018
While the mutational activation of oncogenes drives tumor initiation and growth by promoting cellular transformation and proliferation, increasing evidence suggests that the subsequent re-engagement of largely dormant developmental pathways contributes ...
K. Vandervorst   +4 more
semanticscholar   +1 more source

Modeling the control of planar cell polarity [PDF]

open access: yesWIREs Systems Biology and Medicine, 2011
AbstractA growing list of medically important developmental defects and disease mechanisms can be traced to disruption of the planar cell polarity (PCP) pathway. The PCP system polarizes cells in epithelial sheets along an axis orthogonal to their apical–basal axis.
Jeffrey D, Axelrod, Claire J, Tomlin
openaire   +2 more sources

Rational Fine‐Tuning of MOF Pore Metrics: Enhanced SO2 Capture and Sensing with Optimal Multi‐Site Interactions

open access: yesAdvanced Functional Materials, EarlyView.
A pore tuning strategy to amplify the multi‐site MOF‐SO2 interactions is proposed to achieve an enhanced trace SO2 capture and chemiresistive sensing in highly stable isostructural DMOFs by annelating benzene rings. This work provides a facile strategy to achieve tailor‐made stable MOF materials for specific multifunctional applications.
Shanghua Xing   +9 more
wiley   +1 more source

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