Results 1 to 10 of about 87,879 (288)

Ectopic BASL Reveals Tissue Cell Polarity throughout Leaf Development in Arabidopsis thaliana [PDF]

, 2018
Tissue-wide polarity fields, in which cell polarity is coordinated across the tissue, have been described for planar organs such as the Drosophila wing and are considered important for coordinating growth and differentiation [1].
Chan, Jordi, Coen, Enrico, Hartley, Matthew, Mansfield, Catherine, Newman, Jacob L, Olsson, Tjelvar S G   +5 more
core   +1 more source

Modelling and Analysis of Planar Cell Polarity [PDF]

Bulletin of Mathematical Biology, 2009
Planar cell polarity (PCP) occurs in the epithelia of many animals and can lead to the alignment of hairs, bristles, and feathers. Here, we present two approaches to modelling this phenomenon. The aim is to discover the basic mechanisms that drive PCP, while keeping the models mathematically tractable.
Schamberg, Sabine, Houston, Paul, Monk, Nick A.M., Owen, Markus R.   +3 more
openaire   +4 more sources

LR characterization of chirotopes of finite planar families of pairwise disjoint convex bodies

, 2014
We extend the classical LR characterization of chirotopes of finite planar families of points to chirotopes of finite planar families of pairwise disjoint convex bodies: a map \c{hi} on the set of 3-subsets of a finite set I is a chirotope of finite ...
A Björner, A Hatcher, A Lascoux, B Sturmfels, D Dekker, DC Kay, FB Kalhoff, G Ringel, G Ringel, GK Francis, H Busemann, H Edelsbrunner, H Hadwiger, HR Salzmann, J Bokowski, J Bokowski, J Bokowski, J Cantwell, J Cantwell, J Cantwell, J Folkman, J Goodman, J Groot de, J Stolfi, J-P Doignon, JE Goodman, JE Goodman, JE Goodman, JE Goodman, L Habert, Luc Habert, M Berger, M Drandell, M Haiman, M Novick, M Novick, Michel Pocchiola, P Edelman, R Cordovil, R Dhandapani, R Dhandapani, R Stanley, R Wenger, S Felsner, W Holsztynski, WS Massey   +45 more
core   +1 more source

Mitotic internalization of planar cell polarity proteins preserves tissue polarity [PDF]

Nature Cell Biology, 2011
Planar cell polarity (PCP) is the collective polarization of cells along the epithelial plane, a process best understood in the terminally differentiated Drosophila wing. Proliferative tissues such as mammalian skin also show PCP, but the mechanisms that preserve tissue polarity during proliferation are not understood.
Devenport, Danelle, Oristian, Daniel, Heller, Evan, Fuchs, Elaine   +3 more
openaire   +2 more sources

Planar polarity [PDF]

Organogenesis, 2011
The clinical burden of both adult and neonatal lung disease worldwide is substantial; in the UK alone, respiratory disease kills one in four people. It is increasingly recognized that genes and pathways that regulate lung development, may be aberrantly activated in disease and/or reactivated as part of the lungs' intrinsic repair mechanisms ...
Yates, LL, Dean, CH
openaire   +4 more sources

Reciprocal and dynamic polarization of planar cell polarity core components and myosin

eLife, 2015
The Ciona notochord displays planar cell polarity (PCP), with anterior localization of Prickle (Pk) and Strabismus (Stbm). We report that a myosin is polarized anteriorly in these cells and strongly colocalizes with Stbm.
Erin Newman-Smith, Matthew J Kourakis, Wendy Reeves, Michael Veeman, William C Smith   +4 more
doaj   +1 more source

Patterns in Space: Coordinating Adhesion and Actomyosin Contractility at E-cadherin Junctions

, 2013
Cadherin adhesion receptors are fundamental determinants of tissue organization in health and disease. Increasingly, we have come to appreciate that classical cadherins exert their biological actions through active cooperation with the contractile actin ...
Wu, Selwin K., Yap, Alpha S.
core   +1 more source

Ubiquitin Connects with Planar Cell Polarity [PDF]

Cell, 2009
Planar cell polarity (PCP) regulates the orientation of cells in epithelia and of mesenchymal cells during gastrulation. In this issue, Narimatsu et al. (2009) report that the Smurf E3 ubiquitin ligases are required for localized protein degradation of a core PCP factor to generate cellular asymmetry.
openaire   +2 more sources

Prickle isoforms determine handedness of helical morphogenesis

eLife, 2020
Subcellular asymmetry directed by the planar cell polarity (PCP) signaling pathway orients numerous morphogenetic events in both invertebrates and vertebrates.
Bomsoo Cho, Song Song, Jeffrey D Axelrod
doaj   +1 more source

Planar polarity: Getting ready to ROCK [PDF]

Current Biology, 2001
Cells in the Drosophila wing are polarised to produce a single distally pointing trichome. Recent studies show that this requires the recruitment of the Dishevelled protein to the distal cell edge, and the correct levels of Rho-associated kinase activity.
openaire   +2 more sources