Results 11 to 20 of about 435,658 (283)
Distinct mechanisms of planar polarization by the core and Fat-Dachsous planar polarity pathways in the Drosophila wing [PDF]
Cell Reports, 2022 Planar polarity describes the coordinated polarization of cells within a tissue plane, and in animals can be determined by the “core” or Fat-Dachsous pathways. Current models for planar polarity establishment involve two components: tissue-level “global”
David Strutt +2 more
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Planar Polarity and Tissue Morphogenesis [PDF]
Cell, 2007 Planar polarity is a global, tissue-level phenomenon that coordinates cell behavior in a two-dimensional plane. The Frizzled/planar cell polarity (PCP) and anterior-posterior (AP) patterning systems for planar polarity operate in a variety of cell types and provide direction to cells with different morphologies and behaviors.
Zallen, Jennifer A.
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New insights into regulation and function of planar polarity in the inner ear [PDF]
Neuroscience Letters, 2019 Acquisition of cell polarity generates signaling and cytoskeletal asymmetry and thus underpins polarized cell behaviors during tissue morphogenesis. In epithelial tissues, both apical-basal polarity and planar polarity, which refers to cell polarization ...
Basile Tarchini, Xiaowei Lu
exaly +3 more sources
Nature Communications, 2017 It is unclear if there is an interaction between apical-basal (AB) polarity and planar cell polarity (PCP) pathways during morphogenesis. Here, the authors define a role for the melanoma cell adhesion molecule (MCAM), known to regulate PCP, in AB ...
Qian Gao +11 more
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Planar polarity: Out of joint? [PDF]
Current Biology, 2000 Epithelial structures, such as the wing hairs and ommatidia in Drosophila, are aligned in the plane of the epithelium. This planar polarity requires the transmembrane receptor Frizzled. Recent studies have shed new light on mechanisms that could be involved in generating or transducing the polarity signal.
Bray, Sarah
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The Biological Significance and Implications of Planar Cell Polarity for Nephrology [PDF]
Frontiers in Physiology, 2021 The orientation of cells in two-dimensional and three-dimensional space underpins how the kidney develops and responds to disease. The process by which cells orientate themselves within the plane of a tissue is termed planar cell polarity. In this Review,
Eugenia Papakrivopoulou +5 more
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Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division [PDF]
eLife, 2017 Polarity is a shared feature of most cells. In epithelia, apical-basal polarity often coexists, and sometimes intersects with planar cell polarity (PCP), which orients cells in the epithelial plane. From a limited set of core building blocks (e.g.
Jennifer J Banerjee +5 more
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Cilia Organize Ependymal Planar Polarity [PDF]
The Journal of Neuroscience, 2010 Multiciliated epithelial cells, called ependymal cells, line the ventricles in the adult brain. Most ependymal cells are born prenatally and are derived from radial glia. Ependymal cells have a remarkable planar polarization that determines orientation of ciliary beating and propulsion of CSF.
Mirzadeh, Z +4 more
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Reciprocal action of Casein Kinase Iε on core planar polarity proteins regulates clustering and asymmetric localisation [PDF]
eLife, 2019 The conserved core planar polarity pathway is essential for coordinating polarised cell behaviours and the formation of polarised structures such as cilia and hairs.
Helen Strutt +2 more
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Planar Polarity: Location, Location, Location [PDF]
Current Biology, 2002 Recent studies have shown that many proteins that regulate planar polarity in the fly eye are organized into discrete membrane sites which may be crucial for coordinating groups of cells.
McNeill, Helen, Helen McNeill
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