Results 41 to 50 of about 87,879 (288)

Planar polarity: Out of joint? [PDF]

open access: yesCurrent Biology, 2000
Epithelial structures, such as the wing hairs and ommatidia in Drosophila, are aligned in the plane of the epithelium. This planar polarity requires the transmembrane receptor Frizzled. Recent studies have shed new light on mechanisms that could be involved in generating or transducing the polarity signal.
openaire   +2 more sources

The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea

open access: yesBiology Open, 2015
Hair cells of the organ of Corti (OC) of the cochlea exhibit distinct planar polarity, both at the tissue and cellular level. Planar polarity at tissue level is manifested as uniform orientation of the hair cell stereociliary bundles. Hair cell intrinsic
Anna Kirjavainen   +3 more
doaj   +1 more source

Out-of-surface vortices in spherical shells [PDF]

open access: yes, 2012
The interplay of topological defects with curvature is studied for out-of-surface magnetic vortices in thin spherical nanoshells. In the case of easy-surface Heisenberg magnet it is shown that the curvature of the underlying surface leads to a coupling ...
A. Hubert   +9 more
core   +3 more sources

Planar Cell Polarity Effector Fritz Interacts with Dishevelled and Has Multiple Functions in Regulating PCP

open access: yesG3: Genes, Genomes, Genetics, 2017
The Planar cell Polarity Effector (PPE) genes inturned, fuzzy, and fritz are downstream components in the frizzled/starry night signaling pathway, and their function is instructed by upstream Planar Cell Polarity (PCP) core genes such as frizzled and ...
Ying Wang   +2 more
doaj   +1 more source

PRICKLE1-related early onset epileptic encephalopathy [PDF]

open access: yes, 2018
The PRICKLE1 (Prickle Planar Cell Polarity Protein 1-MIM 608500) gene is involved in different phases of human development. The related diseases include autosomal recessive progressive myoclonus epilepsy - ataxia syndrome, neural tube defects associated ...
DI NOIA, S   +5 more
core   +1 more source

Planar Asymmetries in the C. elegans Embryo Emerge by Differential Retention of aPARs at Cell-Cell Contacts

open access: yesFrontiers in Cell and Developmental Biology, 2019
Formation of the anteroposterior and dorsoventral body axis in Caenorhabditis elegans depends on cortical flows and advection of polarity determinants. The role of this patterning mechanism in tissue polarization after formation of cell-cell contacts is ...
Priyanka Dutta   +2 more
doaj   +1 more source

Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity. [PDF]

open access: yes, 2018
Polarization of the airway epithelial cells (AECs) in the airway lumen is critical to the proper function of the mucociliary escalator and maintenance of lung health, but the cellular requirements for polarization of AECs are poorly understood.
Fahy, John V   +8 more
core   +3 more sources

Arabidopsis  SABRE and CLASP interact to stabilize cell division plane orientation and planar polarity [PDF]

open access: yes, 2013
The orientation of cell division and the coordination of cell polarity within the plane of the tissue layer (planar polarity) contribute to shape diverse multicellular organisms. The root of Arabidopsis thaliana displays regularly oriented cell divisions,
Alonso, J.M.   +8 more
core   +1 more source

Vangl as a Master Scaffold for Wnt/Planar Cell Polarity Signaling in Development and Disease

open access: yesFrontiers in Cell and Developmental Biology, 2022
The establishment of polarity within tissues and dynamic cellular morphogenetic events are features common to both developing and adult tissues, and breakdown of these programs is associated with diverse human diseases. Wnt/Planar cell polarity (Wnt/PCP)
Courtney A. Dreyer   +2 more
doaj   +1 more source

Expression of avian prickle genes during early development and organogenesis [PDF]

open access: yes, 2008
Chicken homologues of prickle-1 (pk-1) and prickle-2 (pk-2) were isolated to gain insight into the extent of planar cell polarity signaling during avian embryogenesis.
Carreira-Barbosa   +40 more
core   +1 more source

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