Results 21 to 30 of about 435,658 (283)
The cell biology of planar cell polarity [PDF]
Journal of Cell Biology, 2014 Planar cell polarity (PCP) refers to the coordinated alignment of cell polarity across the tissue plane. Key to the establishment of PCP is asymmetric partitioning of cortical PCP components and intercellular communication to coordinate polarity between neighboring cells.
Devenport, Danelle, Danelle Devenport
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A systems biology approach to multi-scale modelling and analysis of planar cell polarity in drosophila melanogaster wing [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Systems biology aims to describe and understand biology at a global scale where biological systems function as a result of complex mechanisms that happen at
Gao, Qian
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Frontiers in Aging Neuroscience, 2022 Decline in episodic memory is one of the hallmarks of aging and represents one of the most important health problems facing Western societies. A key structure in episodic memory is the hippocampal formation and the dentate gyrus in particular, as the ...
Muriel Koehl +3 more
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APL Bioengineering, 2023 Vascular endothelial polarity induced by blood flow plays crucial roles in the development of atherosclerosis. Loss of endothelial polarity leads to an increase in permeability and leukocyte recruitment, which are crucial hallmarks of atherosclerotic ...
Kai Qu +6 more
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Frontiers in Cell and Developmental Biology, 2022 Planar cell polarity (PCP) signaling polarizes cells within the plane of an epithelium. In the airways, planar cell polarity signaling orients the directional beating of motile cilia required for effective mucociliary clearance.
Koshi Kunimoto +4 more
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Morphogenetic forces planar polarize LGN/Pins in the embryonic head during Drosophila gastrulation
eLife, 2022 Spindle orientation is often achieved by a complex of Partner of Inscuteable (Pins)/LGN, Mushroom Body Defect (Mud)/Nuclear Mitotic Apparatus (NuMa), Gαi, and Dynein, which interacts with astral microtubules to rotate the spindle.
Jaclyn Camuglia +2 more
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Molecular mechanisms mediating asymmetric subcellular localisation of the core planar polarity pathway proteins. [PDF]
Biochem Soc Trans, 2020 Planar polarity refers to cellular polarity in an orthogonal plane to apicobasal polarity, and is seen across scales from molecular distributions of proteins to tissue patterning.
Harrison C, Shao H, Strutt H, Strutt D.
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Planar cell polarity in Drosophila [PDF]
Organogenesis, 2011 In all multicellular organisms, epithelial cells are not only polarized along the apical-basal axis, but also within the epithelial plane, giving cells a sense of direction. Planar cell polarity (PCP) signaling regulates establishment of polarity within the plane of an epithelium.
Saw Myat Thanda W, Maung, Andreas, Jenny
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The Kidney and Planar Cell Polarity [PDF]
, 2012 Planar cell polarity (PCP) or tissue polarity describes a coordinated polarity at the plane of the tissue where most or all cells within a tissue are polarized in one direction. It is perpendicular to the apical-basal polarity of the cell. PCP is manifested readily in the Drosophila wing and cuticle bristles, Drosophila eye ommatidia, and mammalian ...
Thomas J, Carroll, Jing, Yu
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Afferent neurons of the zebrafish lateral line are strict selectors of hair-cell orientation. [PDF]
PLoS ONE, 2009 Hair cells in the inner ear display a characteristic polarization of their apical stereocilia across the plane of the sensory epithelium. This planar orientation allows coherent transduction of mechanical stimuli because the axis of morphological ...
Adèle Faucherre +3 more
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