Results 21 to 30 of about 87,879 (288)
Planar polarity: converting a morphogen gradient into cellular polarity. [PDF]
Curr Biol, 2015 Epithelial cells are polarized within the apico-basal and planar axes. The latter - planar cell polarity - requires long-range regulation of orientation as well as short-range, cell-to-cell realignment through feedback loops. New insights into the long-range, gradient-type regulation reveal how a kinase translates the morphogen gradient input into ...
Collu GM, Mlodzik M.
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A Dual Function for Prickle in Regulating Frizzled Stability during Feedback-Dependent Amplification of Planar Polarity. [PDF]
Curr Biol, 2017 The core planar polarity pathway coordinates epithelial cell polarity during animal development, and loss of its activity gives rise to a range of defects, from aberrant morphogenetic cell movements to failure to correctly orient structures, such as ...
Warrington SJ +3 more
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Frontiers in Aging Neuroscience, 2022 Decline in episodic memory is one of the hallmarks of aging and represents one of the most important health problems facing Western societies. A key structure in episodic memory is the hippocampal formation and the dentate gyrus in particular, as the ...
Muriel Koehl +3 more
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The Biological Significance and Implications of Planar Cell Polarity for Nephrology
Frontiers in Physiology, 2021 The orientation of cells in two-dimensional and three-dimensional space underpins how the kidney develops and responds to disease. The process by which cells orientate themselves within the plane of a tissue is termed planar cell polarity. In this Review,
Eugenia Papakrivopoulou +5 more
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APL Bioengineering, 2023 Vascular endothelial polarity induced by blood flow plays crucial roles in the development of atherosclerosis. Loss of endothelial polarity leads to an increase in permeability and leukocyte recruitment, which are crucial hallmarks of atherosclerotic ...
Kai Qu +6 more
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Frontiers in Cell and Developmental Biology, 2022 Planar cell polarity (PCP) signaling polarizes cells within the plane of an epithelium. In the airways, planar cell polarity signaling orients the directional beating of motile cilia required for effective mucociliary clearance.
Koshi Kunimoto +4 more
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Morphogenetic forces planar polarize LGN/Pins in the embryonic head during Drosophila gastrulation
eLife, 2022 Spindle orientation is often achieved by a complex of Partner of Inscuteable (Pins)/LGN, Mushroom Body Defect (Mud)/Nuclear Mitotic Apparatus (NuMa), Gαi, and Dynein, which interacts with astral microtubules to rotate the spindle.
Jaclyn Camuglia +2 more
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Cilia Organize Ependymal Planar Polarity [PDF]
The Journal of Neuroscience, 2010 Multiciliated epithelial cells, called ependymal cells, line the ventricles in the adult brain. Most ependymal cells are born prenatally and are derived from radial glia. Ependymal cells have a remarkable planar polarization that determines orientation of ciliary beating and propulsion of CSF.
Z. MIRZADEH +4 more
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Planar cell polarity in Drosophila [PDF]
Organogenesis, 2011 In all multicellular organisms, epithelial cells are not only polarized along the apical-basal axis, but also within the epithelial plane, giving cells a sense of direction. Planar cell polarity (PCP) signaling regulates establishment of polarity within the plane of an epithelium.
Saw Myat Thanda W, Maung, Andreas, Jenny
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Orthogonal planar laser polarization spectroscopy [PDF]
Applied Optics, 2002 Planar laser polarization spectroscopy has recently been used to image the hydroxyl radical in combustion for small intersection angles of pump and probe beams. We report an experimental configuration that allows planar laser polarization imaging for perpendicular intersection of pump and probe beams.
Reppel, J., Alwahabi, Z.
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