Results 61 to 70 of about 13,058,978 (356)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Integrating Optical and SAR Time Series Images for Unsupervised Domain Adaptive Crop Mapping

Remote Sensing
Accurate crop mapping is crucial for ensuring food security. Recently, many studies have developed diverse crop mapping models based on deep learning.
Luwei Feng, Dawei Gui, Shanshan Han, Tianqi Qiu, Yumiao Wang   +4 more
doaj   +1 more source

AI Planning: Systems and Techniques

Ai Magazine, 1990
This article reviews research in the development of plan generation systems. Our goal is to familiarize the reader with some of the important problems that have arisen in the design of planning systems and to discuss some of the many solutions that have been developed in the over 30 years of research in this area.
TateAustin, HendlerJames, DrummondMark
openaire   +4 more sources

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

A survey on smart automated computer-aided process planning (ACAPP) techniques

The International Journal of Advanced Manufacturing Technology, 2018
The concept of smart manufacturing has become an important issue in the manufacturing industry since the start of the twenty-first century in terms of time and production cost.
Mazin Al-Wswasi, A. Ivanov, H. Makatsoris   +2 more
semanticscholar   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Path planning techniques for mobile robots: Review and prospect

Expert systems with applications, 2023
Lixing Liu, Xu Wang, Xin Yang, Hongjie Liu, Jianping Li, Pengfei Wang   +5 more
semanticscholar   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Use of Mathematical Programming Techniques in Production Planning [PDF]

, 1965
Reinhard Kähle
openalex   +2 more sources