Results 111 to 120 of about 1,003,885 (312)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Exploring the Impact of Lipid Structure and Composition on the Digestion of Next-Generation Meat and Dairy Analogues

Foods
The world population is increasing exponentially and is expected to reach 9.2 billion people by 2040, intensifying pressures on food systems and raising concerns regarding food security and environmental sustainability.
Zarnab Asif, Clive A. Prestidge, Paul Joyce   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Effect of Textured Plant Protein Granulation and Presence of Dried Plant Ingredients on Physicochemical Properties of Soy-Based Burger

Molecules
Meat analogues have gained high interest from consumers, food producers and the scientific community due to their potential to be a sustainable alternative to traditional meat products.
Klaudia Kołodziejczak, Klara Żbik, Iwona Wojtasik-Kalinowska, Anna Onopiuk, Andrzej Poltorak   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Educational Presentations Reduce Meat Consumption Across Two Universities

Psychology of Human-Animal Intergroup Relations
Reducing consumption of animal products is crucial to addressing the climate crisis. Educational interventions have shown promise in promoting plant-based diets, but the picture is not yet clear.
Elise Hankins, Chloe Balhatchet, Christopher Bryant, Matti Wilks, Chris Macdonald, Rebecca Hankins, Patience Abugu, Tommy Walker Mackay, William McFarlane Smith, H.-W. Hazel, Sophie Clargo   +10 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structure formation in fruit preparations by fruit fermentates produced with exopolysaccharide-forming lactic acid bacteria

Current Research in Food Science
Fruit preparations are intermediate food products that are primarily used in the dairy industry for the production of fruit yogurt or frozen desserts. Typically, they are stabilized by added hydrocolloids like pectins.
Silvan Festini, Dor Zipori, Marc Wallisch, Agnes Weiss, Sybille Neidhart, Herbert Schmidt, Mario Jekle   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

From personal benefits to green motives: consumer segments for targeted sustainability transitions in workplace canteens

Frontiers in Sustainability
This study came to life through a collaboration between researchers and the service and food industries, aiming for nuanced consumer insights that may inform future sustainability interventions in workplace canteens.
Ragnhild Eg, Antje Gonera, Ida Synnøve Grini, Mads Erling Pedersen, Paula Varela   +4 more
doaj   +1 more source