Results 191 to 200 of about 64,161 (243)

The Potential of Plant-Based Lifestyle Interventions to Reduce the Burden of Disease in a Multi-Crisis Era. [PDF]

Am J Lifestyle Med
Kolandai K, Wright N, Wilson L, Haitjema H, Wright SR, Foster M, Laking G, Kelaher M, Skaria R, Douglas J, Liew MK, Leighton M, Brunt D, Gold-Smith F, Craig M, Joseph T, Hurlow W, Pittar C, Mortimer S.   +18 more
europepmc   +1 more source

Modulating Purothionin Accumulation and Signal Peptide Cleavage Fine‐Tunes Wheat Flour Gluten Properties to Improve Cookie‐Making Quality

Advanced Science, EarlyView.
Dual genetic strategies for improving wheat processing quality by regulating purothionin accumulation to modulate gluten quantity and quality. The first strategy involves targeting signal peptide (SP) cleavage sites (e.g., through mutation) to indirectly reduce gluten content, thereby disrupting gluten network formation.
Yijie Liu, Siyuan Chang, Zhaoheng Zhang, Tianqi Kang, Mingde Liu, Yuan Zong, Fei Ni, Yinguang Bao, Ruijie Zhang, Xiaobang Zhang, Jinkun Du, Mingming Xin, Zhaorong Hu, Jie Liu, Zhongfu Ni, Qixin Sun, Yingyin Yao   +16 more
wiley   +1 more source

Plant-Forward Dietary Approaches to Reduce the Risk of Cardiometabolic Disease Among Hispanic/Latinx Adults Living in the United States: A Narrative Review. [PDF]

Nutrients
De La Calle F, Bagienska J, Beasley JM.
europepmc   +1 more source

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

Advanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang, Renjie Hu, Yanxi Chai, Ping He, Sanduo Li, Lisha Zhao, Wenbin Zhao, Lu Zhang, Li Qin, Ran Li, Xiaoli Hou, Qinghua Sun, Cuiqing Liu   +12 more
wiley   +1 more source

Gut microbiome mediates the association between dietary quality and metabolic risk in a heterogeneous adult population. [PDF]

Nutr Metab (Lond)
Bartsch M, Hemmelrath L, Kerlikowsky F, Bruns A, Burhop M, Nebl J, Greupner T, Strowig T, Lesker TR, Amend L, Vital M, Berkemeyer S, Hahn A, Müller M.   +13 more
europepmc   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Diets optimized for environmental sustainability and health: implications for diet costs across socio-economic positions for Dutch adults. [PDF]

Front Nutr
Vellinga RE, Heerschop SN, Biesbroek S, van 't Veer P, Drijvers J, van Bakel M, Hollander A, Temme EHM.   +7 more
europepmc   +1 more source

The effect of a diet based on vegetable and dairy protein on biochemical and functional indicators of sarcopenia in patients with liver cirrhosis: a randomized controlled trial. [PDF]

Nutr J
Taghizadeh M, Khalese-Ranjbar B, Ostevari A, Taher M, Sohrabpour AA, Yekaninejad MS, Hosseinzadeh-Attar MJ, Asghari S.   +7 more
europepmc   +1 more source

Nutritional Interventions in Osteoarthritis: Mechanisms, Clinical Evidence, and Translational Opportunities. [PDF]

Nutrients
Patel M, Betanzos G, Troka M, Modi J, Nageeb G, Kaye AD, Abd-Elsayed A.   +6 more
europepmc   +1 more source