Results 241 to 250 of about 99,801 (296)

Calcium Channel Blockers Inhibit Pancreatic Neuroendocrine Neoplasms Progression via Cav1.2‐Epigenetic Circuit

Advanced Science, EarlyView.
Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu, Qiongcong Xu, Jinzhao Xie, Mingjian Ma, Xitai Huang, Yinhao Shi, Jiawei Zhou, Enliang Zhu, Ziyi Zhao, Ning Zhang, Zhide Liu, Jingyuan Ye, Xiaoyu Yin   +12 more
wiley   +1 more source

Primary versus secondary production techniques in US manufacturing. [PDF]

Mattey, J., Raa, T. ten
core   +1 more source

Characterization of Plant-Based Milk-Derived "Fujiharu Butter": Comparison With Butter and Butter-Like Substitutes. [PDF]

J Food Sci
Kazama R, Izawa I, Fujiharu K, Misono T, Hoyamatsu Y, Oi N, Tsuno M, Murakami Y, Shono A.   +8 more
europepmc   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

A Mixed-Method Assessment of Drivers and Barriers for Substituting Dairy with Plant-Based Alternatives by Danish Adults. [PDF]

Foods
Philippi Rosane B, Tjørring L, Ley A, Byrne DV, Andersen BV, Bügel SG, Wennerscheid S.   +6 more
europepmc   +1 more source

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

Advanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen, Yahui Gao, Yulin Wang, Ting Lei, Zheng Qu, Yuhan An, Jiaxu Fu, Xin Li, Fangjun Liu, Yan Li   +9 more
wiley   +1 more source

Harmonised assessment of environmental impacts from diets and dietary scenarios: sustainability and protein intake in eleven European countries. [PDF]

Eur J Nutr
Vellinga RE, Sam M, van Donkersgoed G, van Klaveren J, Blaznik U, Rauscher-Gabernig E, Sokolić D, Hamborg Jensen B, Crépet A, Temme EHM.   +9 more
europepmc   +1 more source

Every Person Counts in a Fair Transition to Net Zero: A UK Food Lens Towards Safeguarding Against Nutritional Vulnerability. [PDF]

Nutr Bull
Spiro A, Bardon L, Fanzo J, Hill Z, Stanner S, Traka MH.   +5 more
europepmc   +1 more source

Towards Healthy and Sustainable Diets: Understanding Food Consumption Trends in the EU. [PDF]

Foods
Biganzoli F, Caldeira C, Dias J, De Laurentiis V, Leite J, Wollgast J, Sala S.   +6 more
europepmc   +1 more source

Plant-Based Analogs: Potential Chemical Risks & Mitigation Strategies. [PDF]

J Food Sci
Arinzechukwu C, Tang J, Chen C, Corradini MG.   +3 more
europepmc   +1 more source