Results 101 to 110 of about 532,858 (293)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Molecular and morphometric analyses reveal discrete grouping of pomegranate (Punica granatum) genebank accessions away from cultivars

open access: yesThe Indian Journal of Agricultural Sciences, 2014
Management of germplasm in the field genebanks is greatly assisted by genetic analysis. Estimation of genetic diversity and assessment of genetic relationships among 45 accessions of pomegranate (Punica granatum L.) that included cultivars and germplasm
SUNIL ARCHAK   +6 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Editorial: Wild plant genetic resources: a hope for tomorrow. [PDF]

open access: yesFront Plant Sci, 2023
Khan MK, Islam T, Gezgin S, Di Gioia F.
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Enclosing the Global Plant Genetic Commons [PDF]

open access: yes, 1999
Looks at policies related to the development, use, and control of plant genetic resources, with a focus on property rights in relation to changing technology and its impact on food security in developing ...
Robert W. Herdt
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Comprehensive survey and evolutionary analysis of genome-wide miRNA genes from ten diploid Oryza species

open access: yesBMC Genomics, 2017
Background MicroRNAs (miRNAs) are non-coding RNAs that play versatile roles in post-transcriptional gene regulation. Although much is known about their biogenesis, and gene regulation very little is known about their evolutionary relation among the ...
Showkat Ahmad Ganie   +3 more
doaj   +1 more source

Improving the use of plant genetic resources to sustain breeding programs' efficiency. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Sanchez D   +5 more
europepmc   +1 more source

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