Results 61 to 70 of about 532,858 (293)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

IBPGR: The Strategy [PDF]

, 1988
Strategy paper approved by the IBPGR Board, articulating the strategies and objectives for carrying out the new and expanded mandate approved by the CGIAR in the wake of IBPGR's 1986 external review.
International Board for Plant Genetic Resources
core  

Identification of quantitative trait nucleotides for grain quality in bread wheat under heat stress

Scientific Reports
Heat stress is a critical factor affecting global wheat production and productivity. In this study, out of 500 studied germplasm lines, a diverse panel of 126 wheat genotypes grown under twelve distinct environmental conditions was analyzed.
Latief Bashir, Neeraj Budhlakoti, Anjan Kumar Pradhan, Divya Sharma, Antil Jain, Saman Saim Rehman, Vishal Kondal, Sherry R. Jacob, Rakesh Bhardwaj, Kiran Gaikwad, Dwijesh Chandra Mishra, Abhishek Pandey, Satinder Kaur, Pradeep Kumar Bhati, Rakesh Singh, Gyanendra Pratap Singh, Sundeep Kumar   +16 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Memorandum of Understanding between the Food and Agriculture Organization of the United Nations and the International Plant Genetic Resources Institute concerning the Publication of a Joint Plant Genetic Resources Newsletter [PDF]

, 1994
MOU between FAO and IPGRI signed September 8, 1994 by representatives from both parties . MOU establishes responsibilities between the two parties to produce the successor publication to the FAO/IBPGR Plant Genetic Resources Newsletter.
International Plant Genetic Resources Institute
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Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Memorandum of Understanding between the International Institute of Tropical Agriculture and the International Plant Genetic Resources Institute [PDF]

, 1996
Memorandum of understanding between IITA and IPGRI signed July 24, 1996 in Benin. IITA and IPGRI will develop and execute joint activities on the conservation and use of plant genetic resources of mandate crops of IITA and other crops of national and ...
International Plant Genetic Resources Institute
core  

A gateway to plant genetic resources utilization [PDF]

, 2013
The world is faced with the need to increase crop productivity, develop cultivars that are better adapted to face environmental and biological constraints, and meet the needs of local communities.
Alercia A., Mackay M.
core   +1 more source

Contribution of Dr. Vladimir A. Koshkin to the development of plant physiology at VIR

Труды по прикладной ботанике, генетике и селекции
Vladimir Aleksandrovich Koshkin was a prominent representative of the school of plant physiologists at the N.I. Vavilov All-Russian Institute of Plant Genetic Resources (VIR).
B. V. Rigin, I. G. Loskutov, I. I. Matvienko, Z. A. Shchedrina, R. A. Abdullaev, E. V. Zuev, E. E. Radchenko   +6 more
doaj   +1 more source