Plant-derived vaccines: Advances in delivery approaches [PDF]
Plant CommunicationsHai-Ping Diao +4 more
doaj +2 more sources
Frontiers in Plant Science, 2021 The productivity of major field crops is highly compromised due to weed infestation. Inefficient weed management practices and undue and excessive use of chemical herbicides have drastically contaminated the environment and human health, in addition to ...
Sobia Anwar +5 more
doaj +1 more source
Assessment of bacterial proteome remodeling under virulence-inducing conditions for molecular pharming applications. [PDF]
Microbiol Resour AnnouncKheradvar K +4 more
europepmc +2 more sources
Multi-Omics Identification of Yield Limiting Factors in Molecular Pharming [PDF]
, 2023 Biologics, including protein-based drugs, are among the fastest growing categories of therapeutics under development today. While most biologics are made using mammalian cell systems, plant-based production systems provide a cost-effective approach to ...
Prudhomme, Nicholas
core +2 more sources
Current status and perspectives of the molecular farming landscape [PDF]
, 2022 Art. 20180330, 23 S.This chapter provides an overview of the current state of molecular farming, which is characterized by the development of sizeable production capacities, a greater focus on downstream processing and scale-up, and the targeting of ...
Stöger, E. +3 more
core +1 more source
Rabies virus glycoprotein produced in Nicotiana benthamiana is an immunogenic antigen in mice
Czech Journal of Genetics and Plant Breeding, 2021 Rabies remains an infectious disease among humans and animals, and requires the development of an effective vaccine essential to prevent rabies. Advances in molecular biology and biotechnology have led to the development and improvement of many rabies ...
Youngmin Park +10 more
doaj +1 more source
Cereal crops as viable production and storage systems for pharmaceutical scFv antibodies [PDF]
, 2022 S.583-590This report describes the stable expression of a medically important antibody in the staple cereal crops rice and wheat. We successfully expressed a single-chain Fv antibody (ScFvT84.66) against carcinoembryonic antigen (CEA), a well ...
Christou, P. +10 more
core +1 more source
Plant-based vaccines: Potentiality against severe acute respiratory syndrome coronavirus 2
Biomedical and Biotechnology Research Journal, 2021 The pandemic of novel coronavirus disease-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has stimulated scientists from different backgrounds to gear up on developing vaccines against the virus.
Pramita Sharma +3 more
doaj +1 more source
AgroLux: bioluminescent Agrobacterium to improve molecular pharming and study plant immunity [PDF]
The Plant Journal, 2021 SUMMARY Agroinfiltration in Nicotiana benthamiana is widely used to transiently express heterologous proteins in plants. However, the state of Agrobacterium itself is not well studied in agroinfiltrated tissues, despite frequent ...
Philippe V. Jutras +5 more
openaire +2 more sources
Enabling Transgenic Plant Cell–Derived Biomedicines with Nanotechnology
Advanced NanoBiomed Research, 2021 Transgenic plants are promising factories for manufacturing pharmaceutical small molecules or proteins safe for human consumption. Eukaryotic plant cells can synthesize proteins with precise posttranslational modifications, but microbes cannot ...
Yee Ting Elaine Chiu +1 more
doaj +1 more source