Results 81 to 90 of about 412,560 (308)

Characterising the role of GABA and its metabolism in the wheat pathogen Stagonospora nodorum [PDF]

, 2015
A reverse genetics approach was used to investigate the role of γ-aminobutyric acid metabolism in the wheat pathogenic fungus Stagonospora nodorum. The creation of mutants lacking Sdh1, the gene encoding succinic semialdehyde dehydrogenase, resulted in ...
Mead, Oliver, Solomon, Peter S., Thynne, Eli, Winterberg, Britta   +3 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Functional Transcomplementation between Wheat Dwarf Virus Strains in Wheat and Barley

Viruses, 2019
Wheat dwarf virus, transmitted by the leafhopper Psammotettix alienus in a persistent, non-propagative manner, infects numerous species from the Poaceae family. Data associated with wheat dwarf virus (WDV) suggest that some isolates preferentially infect
Isabelle Abt, Marlène Souquet, Gersende Angot, Romain Mabon, Sylvie Dallot, Gaël Thébaud, Emmanuel Jacquot   +6 more
doaj   +1 more source

Resistant and susceptible pea lines harbour different root-rot pathogens and antagonistic fungi [PDF]

, 2019
Disease resistance encompasses the mechanisms that allow a plant to withstand or ward off a pathogen. The molecular responses of plants under pathogen attack and the underlying genetics have been extensively studied.
Hohmann, Pierre, Messmer, Monika, Studer, Bruno, Wille, Lukas   +3 more
core  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Finished Genome of the Fungal Wheat Pathogen Mycosphaerella graminicola Reveals Dispensome Structure, Chromosome Plasticity, and Stealth Pathogenesis [PDF]

, 2011
The plant-pathogenic fungus Mycosphaerella graminicola (asexual stage: Septoria tritici) causes septoria tritici blotch, a disease that greatly reduces the yield and quality of wheat.
Aerts, A., Antoniw, J., Bailey, A., Bluhm, B., Bowler, J., Bristow, J., Burgt, A., van der, Canto-Canché, B., Churchill, A.C.L., Conde-Ferràez, L., Cools, H.J., Coutinho, P.M., Crane, C.F., Csukai, M., Dehal, P., Dhillon, B., Donzelli, B., Foster, A.J., Geest, H.C., van de, Goodwin, S.B., Grigoriev, I.V., Grimwood, J., Ham, R.C.H.J., van, Hammond-Kosack, K.E., Hane, J.K., Henrissat, B., Kema, G.H.J., Kilian, A., Kobayashi, A.K., Koopmann, E., Kourmpetis, Y., Kuzniar, A., Lee, T.A.J., van der, Lindquist, E., Lombard, V., M'Barek, S., Ben, Maliepaard, C.A., Martins, N., Mehrabi, A., Nap, J.P.H., Oliver, R.P., Ponomarenko, A., Rudd, J.J., Salamov, A., Schmutz, J., Schouten, H.J., Shapiro, H., Stergiopoulos, I., Torriani, S.F.F., Tu, H., Vries, R.P., de, Waalwijk, C., Ware, S.B., Wiebenga, A., Wit, P.J.G.M., de, Wittenberg, A.H.J., Zwiers, L.H.   +56 more
core   +5 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Compensating damage effects of seed-borne Fusarium culmorum and Microdochium nivale in winter wheat by increased seeding rates [PDF]

, 2005
Fusarium culmorum and Microdochium nivale are considered important seed-borne diseases of wheat in Denmark. Their damage effects consist in reducing seed germination and plant emergence which leads to reduced plant density, panicle numbers/area and yield.
Justesen, A.F., Pinnschmidt, H.O.
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

PathOrganic – Risks and Recommendations Regarding Human Pathogens in Organic Vegetable Production Chains [PDF]

, 2009
PathOrganic assesses risks associated with the consumption of fresh and minimally processed vegetables due to the prevalence of bacterial human pathogens in plant produce.
Arthurson, V., Baggesen, D., Brankatschk, K., Dalsgaard, A., Duffy, B., Fenzl, C., Friedel, J.K., Hackl, E., Hartmann, A., Hedin, F., Hofmann, A., Jansson, J., Jensen, A.N., Jäderlund, L., Koller, M., Mäder, P., Rinnofner, T., Schmid, M., Sessitsch, A., Storm, C., van Bruggen, A.H.C., Widmer, F., Wyss, G.S., Zijlstra, C.A.   +23 more
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