MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Commodity risk assessment of <i>Salix</i> unrooted cuttings from the UK. [PDF]
EFSA Panel on Plant Health (PLH) +29 more
europepmc +1 more source
Genetically Engineered Crops: How the Courts Dismantled the Doctrine of Substantial Equivalence [PDF]
Findley, Trevor
core +1 more source
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Complete biosynthesis of psychedelic tryptamines from three kingdoms in plants. [PDF]
Berman P +15 more
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Structural diversity of isoprene synthases in mosses from multiple terpenoid synthase lineages. [PDF]
Kawakami T +3 more
europepmc +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Plant-Based Diet Quality and Gastric Cancer Risk: A Case-Control Study in High-Risk Regions of Fujian Province, China. [PDF]
Chen X +7 more
europepmc +1 more source
Correction: Khan et al. Plant Secondary Metabolites-Central Regulators Against Abiotic and Biotic Stresses. <i>Metabolites</i> 2025, <i>15</i>, 276. [PDF]
Khan A +7 more
europepmc +1 more source

