Results 101 to 110 of about 55,475 (331)
Advanced Science, EarlyView.This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su +18 more
wiley +1 more source
The Cdc42 effectors Ste20, Cla4, and Skm1 down-regulate the expression of genes involved in sterol uptake by a mitogen-activated protein kinase-independent pathway [PDF]
, 2009 © 2009 by The American Society for Cell Biology. Under the License and Publishing Agreement, authors grant to the general public, effective two months after publication of (i.e.,.
Höfken, Thomas +5 more
core +2 more sources
Poria cocos as a Functional Food for Diabetes and Diabetes‐Related Foot Ulcers
AgriFood: Journal of Agricultural Products for Food, EarlyView.Poria cocos is known as an edible mushroom for food and medicine. Poria cocos and its terpenes and terpenoids serve as novel remedies to treat diabetes and its ulcers. Its mode of actions includes reduction of insulin resistance, starch digestion and inflammation as well as promotion of blood vessel formation. ABSTRACT Poria cocos is a medicinal fungus
Yi‐San Lee +3 more
wiley +1 more source
Consumption Habits of Low-Fat Plant Sterol-Enriched Yoghurt Enriched with Phytosterols
, 2014 M. J. Reis Lima +4 more
+4 more sources
Guidelines for the Anti‐Obesity Assays of Food Bioactives in Caenorhabditis elegans
AgriFood: Journal of Agricultural Products for Food, EarlyView.This Guideline uses Caenorhabditis elegans as a model organism to systematically explain and summarize the research strategies and experimental methods for the anti‐obesity effects of food bioactives. ABSTRACT The obesity has become a global public health problem and is closely related to a variety of chronic diseases.
Rui Lu
wiley +1 more source
Journal of Lipid Research, 2009 Changes in the balance of cholesterol absorption and synthesis and moderately elevated plasma plant sterols have been suggested to be atherogenic. Measuring cholestanol, lathosterol, campesterol, and sitosterol, we investigated the relationships of ...
Guenther Silbernagel +7 more
doaj +1 more source
Plant Sterols and Plant Stanols in Cholesterol Management and Cardiovascular Prevention. [PDF]
Nutrients, 2023 Barkas F +5 more
europepmc +1 more source
Inhibition of geranylgeranyl diphosphate synthesis in in vitro systems [PDF]
, 1985 The incorporation of [14C]mevalonate and [14C]isopentenyl diphosphate into geranylgeranyl diphosphate was investigated in in vitro systems from Cucurbita pepo (pumpkin) endosperm and from Avena sativa etioplasts.
Mitzka-Schnabel, Ursula +4 more
core +1 more source
Animal Models and Experimental Medicine, EarlyView.An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen +12 more
wiley +1 more source
Apolipoprotein E Genetic Variant and Blood Lipid Responses to Plant Sterols: A Systematic Review and Pooled Analysis of Clinical Trials. [PDF]
Prev Nutr Food Sci, 2023 Abumweis S, Alzyoud L, Alqadi S.
europepmc +1 more source