Results 41 to 50 of about 4,144,699 (329)

Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC

Toxins, 2022
The compound EACC (ethyl (2-(5-nitrothiophene-2-carboxamido) thiophene-3-carbonyl) carbamate) was recently reported to inhibit fusion of autophagosomes with lysosomes in a reversible manner by inhibiting recruitment of syntaxin 17 to autophagosomes.
Kirsten Sandvig, Simona Kavaliauskiene, Anne Grethe Myrann, Tore Geir Iversen, Tore Skotland   +4 more
doaj   +1 more source

Ptaquiloside and Pterosin B Levels in Mature Green Fronds and Sprouts of Pteridium arachnoideum

Toxins, 2020
Pteridium arachnoideum, a fern of the Pteridium aquilinum species complex found in South America, is responsible for several different syndromes of poisoning.
Debora da Silva Freitas Ribeiro, Kelly Moura Keller, Benito Soto-Blanco   +2 more
doaj   +1 more source

Insight into the Impact of Food Processing and Culinary Preparations on the Stability and Content of Plant Alkaloids Considered as Natural Food Contaminants

Applied Sciences, 2023
Pyrrolizidine alkaloids, tropane alkaloids and opium alkaloids are natural plant toxins that have recently gained special interest in food safety due to their concerning occurrence in many foods and feeds.
Natalia Casado, Gema Casado-Hidalgo, Lorena González-Gómez, Sonia Morante-Zarcero, Isabel Sierra   +4 more
doaj   +1 more source

Global Challenges and Solutions in the early Warning, Monitoring and Toxicity Assessment of Biotoxins in the Food and Feed Chain

Liang you shipin ke-ji, 2021
There is a massive and urgent need to ensure safety and security of the food supply of the world´s growing population. However, global agriculture and food industries continue to be vulnerable to problems of contamination with biotoxins produced by ...
Rudolf Krska, Eskola Mari , BERTHILLER Franz, NIELEN Michel, OSWALD Isabelle, ELLIOTT Chris, MCNERNEY Oonagh, BOTANALUIS Miguel, MALACHOVÁ Alexandra   +8 more
doaj   +1 more source

Plant toxins: alkaloids and their toxicities

, 2018
Since ancient civilization, plants have been utilized in many aspects of life, especially in medicinal purposes due to the presence of distinctive secondary metabolites like alkaloids, phenolics and terpenoids.
Kamarul Zaman Munirah Adibah, Mohamad Azzeme Azzreena   +1 more
semanticscholar   +1 more source

Plant Insecticidal Toxins in Ecological Networks

Toxins, 2012
Plant secondary metabolites play a key role in plant-insect interactions, whether constitutive or induced, C- or N-based. Anti-herbivore defences against insects can act as repellents, deterrents, growth inhibitors or cause direct mortality.
Sébastien Ibanez, Christiane Gallet, Laurence Després   +2 more
doaj   +1 more source

UPLC-MS/MS Analysis of Hydroxyanthracene Derivatives in Botanical Food Products and Supplements: Surveillance of the Italian Market

Foods
Hydroxyanthracene derivatives (HADs) are natural compounds that occur in several botanical species belonging to the genera Aloe L., Cassia L., Rheum L., Frangula Mill., and Rhamnus L.
Mariantonietta Peloso, Alessandro Capriotti, Damiano Accurso, Elena Butovskaya, Giorgio Fedrizzi, Elisabetta Caprai   +5 more
doaj   +1 more source

Overview of available toxicity data for calystegines

EFSA Journal, 2019
Calystegines are polyhydroxylated nortropane alkaloids that have been found in various solanaceous foods, in particular in potatoes and aubergines. The biological activity and potential toxicity of calystegines are associated with their capacity to ...
European Food Safety Authority (EFSA), Marco Binaglia, Katleen Baert, Marijke Schutte, Rositsa Serafimova   +4 more
doaj   +1 more source

Hosts and Heterologous Expression Strategies of Recombinant Toxins for Therapeutic Purposes

Toxins, 2023
The production of therapeutic recombinant toxins requires careful host cell selection. Bacteria, yeast, and mammalian cells are common choices, but no universal solution exists.
Luana di Leandro, Martina Colasante, Giuseppina Pitari, Rodolfo Ippoliti   +3 more
doaj   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source