Results 21 to 30 of about 2,579,616 (291)
New Insights on Saporin Resistance to Chemical Derivatization with Heterobifunctional Reagents
Saporin is a type 1 ribosome-inactivating protein widely used as toxic payload in the construction of targeted toxins, chimeric molecules formed by a toxic portion linked to a carrier moiety.
Massimo Bortolotti +4 more
doaj +1 more source
Effects of Alternaria alternata f.sp. lycopersici toxins on pollen [PDF]
Effects of the phytotoxic compounds (AAL-toxins) isolated from cell-free culture filtrates of Alternaria alternata f.sp. lycopersici on in vitro pollen development were studied. AAL-toxins inhibited both germination and tube growth of pollen from several
Franken, J. +9 more
core +2 more sources
The effect of Staphylococcus aureus carriage in late pregnancy on antibody levels to staphylococcal toxins in cord blood and breast milk. [PDF]
We investigated the effect of carriage of Staphylococcus aureus in the later stages of pregnancy on levels of antibody specific to the S. aureus toxins, staphylococcal enterotoxin B (SEB), staphylococcal enterotoxin C (SEC) and toxic shock syndrome toxin-
Morris, James A. +3 more
core +4 more sources
Ricin: An Ancient Story for a Timeless Plant Toxin
The castor plant (Ricinus communis L.) has been known since time immemorial in traditional medicine in the pharmacopeia of Mediterranean and eastern ancient cultures. Moreover, it is still used in folk medicine worldwide.
Letizia Polito +4 more
doaj +1 more source
Plants respond to pest attack, among other mechanisms, by producing specific proteins with insecticidal properties. Proteins with toxic effects on insects have also been discovered in many other organisms, especially fungi and bacteria.
Primož ŽIGON +2 more
doaj +1 more source
Tomato resistance to Alternaria stem canker: localization in host genotypes and functional expression compared to non-host resistance [PDF]
The Alternaria stem canker resistance locus (Asc-locus), involved in resistance to the fungal pathogen Alternaria alternata f. sp. lycopersici and in insensitivity to host-specific toxins (AAL-toxins) produced by the pathogen, was genetically mapped on ...
Witsenboer, H.M.A., +9 more
core +2 more sources
Ricin trafficking in plant and mammalian cells [PDF]
Ricin is a heterodimeric plant protein that is potently toxic to mammalian and many other eukaryotic cells. It is synthesized and stored in the endosperm cells of maturing Ricinus communis seeds (castor beans).
Lord, Mike +3 more
core +1 more source
Microbial degradation of plant toxins
Abstract Plants produce a variety of secondary metabolites in response to biotic and abiotic stresses. Although they have many functions, a subclass of toxic secondary metabolites mainly serve plants as deterring agents against herbivores, insects, or pathogens.
Magda A. Rogowska‐van der Molen +4 more
openaire +3 more sources
Streptavidin-Saporin: Converting Biotinylated Materials into Targeted Toxins
Streptavidin-Saporin can be considered a type of ‘secondary’ targeted toxin. The scientific community has taken advantage of this conjugate in clever and fruitful ways using many kinds of biotinylated targeting agents to send saporin into a ...
Denise Higgins +4 more
core +1 more source
Ribosome-Inactivating Proteins from Plants: A Historical Overview
This review provides a historical overview of the research on plant ribosome-inactivating proteins (RIPs), starting from the first studies at the end of eighteenth century involving the purification of abrin and ricin, as well as the immunological ...
Andrea Bolognesi +4 more
doaj +1 more source

