Results 51 to 60 of about 2,579,616 (291)

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Hosts and Heterologous Expression Strategies of Recombinant Toxins for Therapeutic Purposes

Toxins, 2023
The production of therapeutic recombinant toxins requires careful host cell selection. Bacteria, yeast, and mammalian cells are common choices, but no universal solution exists.
Luana di Leandro, Martina Colasante, Giuseppina Pitari, Rodolfo Ippoliti   +3 more
doaj   +1 more source

Evaluation of agronomic practices for mitigation of natural toxins. [PDF]

, 2010
Several preventive and corrective measures to minimize toxin contamination in agricultural commodities particularly by mycotoxins have been attempted.
Hardy, Anthony, Riemens, Marleen, Alink, G.M., Magan, N., Pilegaard, K., Battilani, Paola, Alink, Gerrit, Speijers, G., de Saeger, S., Speijers, Gerrit, Battilani, P., de Saeger, Sarah, Saeger, S., de, Magan, Naresh, Hardy, A., Pilegaard, Kirsten, Riemens, M.M.   +16 more
core  

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Occurrence of Beauvericin in Corn from Croatia

Food Technology and Biotechnology, 2002
The occurrence of beauvericin has been investigated in corn kernel (Zea mays L.) samples collected in 1996 (105 samples) and 1997 (104 samples) from 14 corn-producing counties of Croatia. Corn sample extracts were cleaned up by silica gel minicolumns and
Michele Solfrizzo, Bogdan Cvjetkovic, Analisa De Girolamo, Angelo Visconti, Zeljko Jurjevic   +4 more
doaj  

Antibodies and Vaccines Against Botulinum Toxins: Available Measures and Novel Approaches

, 2019
International audienceBotulinum neurotoxin (BoNT) is produced by the anaerobic, Gram-positive bacterium Clostridium botulinum. As one of the most poisonous toxins known and a potential bioterrosism agent, BoNT is characterized by a complex mode of action
Rasetti-Escargueil, Christine, Michel R. Popoff, Popoff, Michel, Christine Rasetti-Escargueil   +3 more
core   +1 more source

Dominant negative phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba mutants suggest hetero-oligomer formation among different Cry toxins. [PDF]

, 2011
Background - Bacillus thuringiensis Cry toxins are used worldwide in the control of different insect pests important in agriculture or in human health. The Cry proteins are pore-forming toxins that affect the midgut cell of target insects.
Leivi Portugal, Maagd, R.A., de, Daniela Carmona, Alejandra Bravo, Portugal, L., de Maagd, R.A., Bakker, P., Perez, C., Claudia Rodríguez-Almazán, Mario Soberón, Bravo, A., Rodriguez-Almazan, C., Carmona, D., Claudia Pérez, Soberon, M., Carlos Muñoz-Garay, Ruud A de Maagd, Munoz-Garay, C., Petra Bakker   +18 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source