Results 141 to 150 of about 77,880 (309)
Does having bad epilepsy make you a good surgical candidate? A number needed to treat analysis
Epilepsia Open, EarlyView.Abstract Epilepsy surgery is an established treatment for drug‐resistant epilepsy, offering a realistic prospect of seizure freedom in well‐selected candidates. However, surgery is sometimes offered to individuals with a low probability of seizure freedom when it is framed as potentially “life‐saving” on the basis of the elevated mortality associated ...
Sallie Baxendale +2 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract This multicenter retrospective study evaluated the effectiveness and safety of highly purified cannabidiol (CBD) in 22 patients with 15q11.2‐q13.1 duplication or deletion syndromes (15q‐DDS), including 12 with 15q duplication syndrome (dup15q) and 10 with Angelman syndrome (AS). Median (interquartile range [IQR]) age at CBD initiation was 14.5
Emanuele Cerulli Irelli +14 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Objective To investigate the frequency, predictors, and clinical implications of diagnostic reassessment in patients previously diagnosed with childhood‐onset epilepsy during the transition period to adult care at a tertiary epilepsy center. Methods We conducted a retrospective cohort study of 317 patients previously diagnosed with childhood ...
Tetsuhiro Fukuyama +9 more
wiley +1 more source
Chronic sleep deprivation promotes drug‐resistant epilepsy via the BMAL1‐mTOR‐P‐gp axis
Epilepsia Open, EarlyView.Abstract Objective The interplay between chronic sleep deprivation and drug‐resistant epilepsy (DRE) has gained increasing attention. Brain and muscle Arnt‐like protein 1 (BMAL1), which is implicated in sleep disturbance, has an unclear role in DRE. We aimed to investigate the role of BMAL1 in sleep deprivation‐induced DRE. Methods A pentylenetetrazole
Xiaomeng Wang +7 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background A handheld smartphone‐based computer vision algorithm (RealHorse® [RH]) offers accessible alternatives for equine gait analysis but requires validation against a gold‐standard three‐dimensional multicamera optical motion capture system (Qualisys® [QS]).
Karsten Key +4 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Bone grafting in equine medicine offers a promising contribution to treating orthopaedic developmental diseases and chondral, osteochondral and segmental bone defects. Among grafts, synthetic bone substitutes—alloplastics—show favourable biological properties addressing numerous limitations presented by autografts, xenografts and ...
Katarzyna Skierbiszewska +6 more
wiley +1 more source
Food Chemistry International, EarlyView.Boiling retained the nutrients and polyphenol compounds in Plectranthus esculentus tubers better than frying or roasting. A bioavailability study showed that the phytates and oxalates in the tuber may not affect the bioavailabilities of calcium, zinc, or iron in Plectranthus esculentus tubers when eaten.
Mercy Amarachi Iroaganachi +4 more
wiley +1 more source
Food Chemistry International, EarlyView.Composite sourdough breads were developed from blends of unripe plantain, tiger nut, and fenugreek flours. Optimized formulations improved pasting stability and enhanced texture, producing softer more elastic crumbs. The enriched breads contained higher dietary fiber and bioactive compounds, and significantly reduced serum cholesterol markers ...
Mary T. Ademosun +4 more
wiley +1 more source
Food Biomacromolecules, EarlyView.Abstract The present work aimed to evaluate the effect of different isolation methods (distilled water, sodium hydroxide, and potassium metabisulfite) on the properties of plantain starch and compared with flour. It was hypothesized that chemical steeping enhanced yield, techno‐functional properties, and resistant starch without disrupting native ...
Tanvir Ahmed Laskar +3 more
wiley +1 more source
Food Safety and Health, EarlyView.This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi +6 more
wiley +1 more source