Results 131 to 140 of about 247,007 (308)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Cut–dip–budding delivery system enables genetic modifications in plants without tissue culture

open access: yesThe Innovation, 2023
Of the more than 370 000 species of higher plants in nature, fewer than 0.1% can be genetically modified due to limitations of the current gene delivery systems.
Xuesong Cao   +12 more
doaj  

Resistance of genetically modified potatoes to Potato virus Y under field conditions Resistência de plantas de batata geneticamente modificadas ao Potato virus Y em condições de campo

open access: yesPesquisa Agropecuária Brasileira, 2009
The objective of this work was to evaluate the resistance of genetically modified clones of potato to Potato virus Y (PVY) under field conditions. Genetically modified plants were compared with nontransformed plants of the same cultivar.
André Nepomuceno Dusi   +3 more
doaj   +1 more source

GENETICALLY MODIFIED PLANTS WITH ENHANCED RESISTANCE TO FUNGAL DISEASES AND A METHOD OF PRODUCTION THEREOF [PDF]

open access: yes, 2003
The present invention discloses genetically modified plants, such as potato plants. The plants are more resistant to a pathogen of interest following transformation of plant cells with a chimeric gene comprising a chitinase gene and beta-1,3-glucanase ...

core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

THE USE OF TRANSGENIC PLANTS FOR THE DEVELOPMENT OF SELECTED BIOPRODUCTS – ACHIEVEMENTS OF THE POLISH SCIENTISTS

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2013
Green biotechnology plays an important role in the modern agriculture. Recent progress in molecular biology and genetic engineering provides an opportunity of obtaining transgenic plants with improved characteristics, such as yield parameters ...
Magda Zapalska, Krzysztof Kowalczyk
doaj  

Impact of genetically modified organisms on meat quality

open access: yesOpen Veterinary Journal
A unique class of gene biotechnology known as genetic modification modifies the genetic makeup of living things like microbes, plants, and animals. Several possible advantages and hazards associated with gene biotechnology. Due to increased food demands
Muntaha Ghazi Hasan
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Non-Destructive Carotenoid Quantification in Leaves via Raman Spectroscopy: Optimizing Treatment for Linear Discriminant Analysis [PDF]

open access: yesarXiv
This study introduces a novel method for quantifying challenging carotenoids in leaf tissues, which typically produce less stable signals than fruits, grains, and roots, by applying Linear Discriminant Analysis (LDA) modeling to interpret Raman spectroscopy data.
arxiv  

Gene diffusion and Safety of transgenic Genetically Modified plants [PDF]

open access: yes, 2010
遺伝子組み換え植物である,グリホサート耐性遺伝子組換えダイズ(Glicine max)(モンサント社のT. MON2)を用いて遺伝子拡散と土壌微生物相への影響について検討した。2004年の圃場試験では非組換えダイズとしてタンレイを用いて距離80cmまで0.115%の確率で,2005年の圃場試験では非組換えダイズとしてタンレイ,スズユタカを用いてタンレイでのみ距離140cmまで0.018%の確率で花粉の飛散による遺伝子拡散が認められた。遺伝子組換えダイズの土壌微生物相への影響は希釈培養法で検討した ...
三枝 正彦   +2 more
core   +1 more source

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