The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability
Mediators of Inflammation, 2020 Matrix metalloproteinase-9 (MMP-9) belongs to the MMP family and has been widely investigated. Excessive MMP-9 expression can enhance extracellular matrix degradation and promote plaque instability.
Tiewei Li +5 more
doaj +2 more sources
Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque [PDF]
Scientific Reports, 2018 Experimental studies showed that gut-derived lipopolysaccharide (LPS) is pro-atherogenic, however, its relationship with human atherosclerosis is still to be defined.
Cammisotto, Vittoria +11 more
core +3 more sources
Neovascularization in Atherosclerotic Plaques: Clinical Implications, Detection, and Prevention Strategies [PDF]
Reviews in Cardiovascular MedicineFollowing the global increase in atherosclerotic cardiovascular diseases, the demand for the effective identification of high-risk factors that lead to atherosclerotic plaque rupture and the search for new therapeutic targets has also increased ...
Long Zhang +4 more
doaj +2 more sources
Coronary Artery Disease and Atherosclerosis in Other Vascular Districts: Epidemiology, Risk Factors and Atherosclerotic Plaque Features [PDF]
LifeCoronary artery disease (CAD) is the main cause of morbidity and death worldwide, and atherosclerosis represents the leading pathophysiological pathway responsible for CAD.
Michele Russo +11 more
doaj +2 more sources
Chronic miR‐29 antagonism promotes favorable plaque remodeling in atherosclerotic mice
EMBO Molecular Medicine, 2016 Abnormal remodeling of atherosclerotic plaques can lead to rupture, acute myocardial infarction, and death. Enhancement of plaque extracellular matrix (ECM) may improve plaque morphology and stabilize lesions.
Victoria Ulrich +18 more
doaj +2 more sources
Angiogenesis in the atherosclerotic plaque
Redox Biology, 2017 Atherosclerosis is a multifocal alteration of the vascular wall of medium and large arteries characterized by a local accumulation of cholesterol and non-resolving inflammation. Atherothrombotic complications are the leading cause of disability and mortality in western countries.
Caroline Camaré +3 more
semanticscholar +4 more sources
Calcifications in atherosclerotic plaques and impact on plaque biomechanics.
Journal of Biomechanics, 2019 The catastrophic mechanical rupture of an atherosclerotic plaque is the underlying cause of the majority of cardiovascular events. The infestation of vascular calcification in the plaques creates a mechanically complex tissue composite. Local stress concentrations and plaque tissue strength properties are the governing parameters required to predict ...
H. Barrett +4 more
semanticscholar +4 more sources
Effects of lipid-lowering therapy on coronary atherosclerotic plaque evaluated by intravascular imaging [PDF]
Jichu yixue yu linchuang, 2022 The progression of atherosclerotic plaque is one of the most important causes of cardiovascular events in patients with atherosclerotic cardiovascular diseases (ASCVD).
ZHANG Shuang, LI Zhi-fan, QIAN Jie, WU Na-qiong
doaj +1 more source
Inflammation during the life cycle of the atherosclerotic plaque.
Cardiovascular Research, 2021 Inflammation orchestrates each stage of the life cycle of atherosclerotic plaques. Indeed, inflammatory mediators likely link many traditional and emerging risk factors with atherogenesis.
P. Libby
semanticscholar +1 more source
Advances of nanoparticle-mediated diagnostic and theranostic strategies for atherosclerosis
Frontiers in Bioengineering and Biotechnology, 2023 Atherosclerotic plaque remains the primary cause of morbidity and mortality worldwide. Accurate assessment of the degree of atherosclerotic plaque is critical for predicting the risk of atherosclerotic plaque and monitoring the results after intervention.
Lin Lin +19 more
doaj +1 more source