Results 111 to 120 of about 39,266 (270)

Refractory Eczema as a Presenting Feature of Common Variable Immunodeficiency

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic inborn error of immunity (IEI) in adults. It presents with recurrent infections and non‐infectious complications, including autoimmunity, lymphoproliferation and dermatitis.
Mercedes Sanchez‐Diaz   +2 more
wiley   +1 more source

Clinico-epidemiological study of childhood psoriasis

open access: yesBangabandhu Sheikh Mujib Medical University Journal, 2017
The clinico-epidemiological data of 276 childhood psoriasis were studied. The mean age was 7.64 years (range 1 day to 15 years). There was no complain of any discomfort in 198 cases. Itching was present in 67 cases and burning in 11 cases.
Mohammed Saiful Islam Bhuiyan   +4 more
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Metabolic dysfunction associated steatotic liver disease in patients with plaque psoriasis: a case–control study and serological comparison

open access: yesFrontiers in Medicine
BackgroundThe relationship between plaque psoriasis and both MASLD and lean MASLD has not been sufficiently explored in the current literature.MethodThis retrospective and observational study was carried out from January 2021 to January 2023 at The First
Zheng Lin   +7 more
doaj   +1 more source

Mycosis Fungoides Is a Proliferation of Multiple Mutational Subclones

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Mycosis fungoides (MF) is a unique type of lymphoma with an excellent prognosis presenting with a wide variety of clinical and histological findings. Recent sophisticated research techniques have revealed that very slow changes in the clinical and histological pictures of one patient over time are due to intratumoral heterogeneity.
Ryoma Honda   +2 more
wiley   +1 more source

Highlighting Interleukin-36 Signalling in Plaque Psoriasis and Pustular Psoriasis

open access: yesActa Dermato-Venereologica, 2017
Plaque psoriasis and pustular psoriasis are overlapping, but distinct, disorders. The therapeutic response to biologics supports the pivotal role of the tumour necrosis alpha (TNF-?)/ interleukin (IL)-23/IL-17/IL-22 axis in the pathogenesis of these ...
Kazuhisa Furue   +8 more
doaj   +1 more source

2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells. [PDF]

open access: yes, 2019
The present paradigm of psoriasis pathogenesis revolves around the IL-23/IL-17A axis. Dual-secreting Th17 T cells presumably are the predominant sources of the psoriasis phenotype-driving cytokines, IL-17A and IL-22.
Adamopoulos, Iannis E   +12 more
core  

The metabolomics of psoriatic disease. [PDF]

open access: yes, 2017
Metabolomics is an emerging new "omics" field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes ...
Afifi, Ladan   +6 more
core  

Circumscribed Morphea Successfully Treated With Excimer Laser: Analysis of Histopathological Changes

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Localized scleroderma (LSc) is an autoimmune condition characterized by localized cutaneous sclerosis, sometimes extending into deeper tissues. Phototherapy, including excimer laser therapy (ELT), is considered an effective and minimally invasive treatment option for patients without extracutaneous involvement.
Takuya Takahashi   +5 more
wiley   +1 more source

Chronic plaque psoriasis

open access: yesPAMJ Clinical Medicine, 2022
Trupti Thakre, Sourabh Deshmukh
openaire   +1 more source

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