Results 101 to 110 of about 162,485 (319)

Application of biologics for ridge preservation/reconstruction after implant removal

Clinical Advances in Periodontics, Volume 12, Issue 4, Page 270-276, December 2022., 2022
Abstract Background The purpose of this review was aimed at providing the rationale supported with a series of cases to apply biologics to enhance orchestrating the healing process at implant removal sites. Summary Implant removal is commonly applied on a daily basis, in particular, in cases that exhibit esthetic failures linked to inadequate implant ...
Alberto Monje, Fernando Suárez‐López del Amo   +1 more
wiley   +1 more source

Sphingosine kinase regulates oxidized low density lipoprotein-mediated calcium oscillations and macrophage survival

Journal of Lipid Research, 2010
We recently reported that oxidized LDL (oxLDL) induces an oscillatory increase in intracellular calcium ([Ca2+]i) levels in macrophages. Furthermore, we have shown that these [Ca2+]i oscillations mediate oxLDL's ability to inhibit macrophage apoptosis in
Johnny H. Chen, Maziar Riazy, Shih Wei Wang, Jiazhen Minnie Dai, Vincent Duronio, Urs P. Steinbrecher   +5 more
doaj  

Inhibiting Integrin α5 Cytoplasmic Domain Signaling Reduces Atherosclerosis and Promotes Arteriogenesis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundFibronectin in endothelial basement membranes promotes endothelial inflammatory activation and atherosclerosis but also promotes plaque stability and vascular remodeling. The fibronectin receptor α5 subunit is proinflammatory through binding to
Madhusudhan Budatha, Jiasheng Zhang, Zhen W. Zhuang, Sanguk Yun, James E. Dahlman, Daniel G. Anderson, Martin A. Schwartz   +6 more
doaj   +1 more source

P710S100A4, a key player in plaque stabilization?

European Heart Journal, 2019
Abstract During atherosclerosis, intimal smooth muscle cells (SMCs) acquire a synthetic phenotype. We previously isolated spindle-shaped (S) and rhomboid (R) SMCs from porcine coronary artery. R-SMCs display the features of synthetic/dedifferentiated SMCs. S100A4 was identified as being a marker of R-
Marie-Luce Bochaton-Piallat, Antonija Sakic, Noona Ambartsumian, Brenda R. Kwak, Jörg Klingelhöfer, M Grigorian   +5 more
openaire   +2 more sources

Development of Carbon‐11 Labeled Pyrimidine Derivatives as Novel Positron Emission Tomography (PET) Agents Enabling Brain Sigma‐1 Receptor Imaging

Advanced Science, EarlyView.
Novel carbon‐11 labeled pyrimidine derivatives are developed as PET imaging probes for visualizing sigma‐1 receptors in the brain. [11C]CNY‐01 demonstrates superior brain uptake and binding specificity in both rodents and non‐human primates. The study reveals decreased sigma‐1 receptor expression in Alzheimer's disease, offering a promising tool for ...
Ping Bai, Ashley Gomm, Chi‐Hyeon Yoo, Prasenjit Mondal, Fleur Marie Lobo, Hui Meng, Yanting Zhou, Weiyao Xie, Hsiao‐Ying Wey, Rudolph E. Tanzi, Can Zhang, Changning Wang, Yu Lan   +12 more
wiley   +1 more source

Syntaxin 17 Translocation Mediated Mitophagy Switching Drives Hyperglycemia‐Induced Vascular Injury

Advanced Science, EarlyView.
Mitophagy switching drives high‐glucose‐induced vascular endothelial injury. Short‐term high‐glucose exposure upregulates Fis1 expression and enhances Fis1‐TBC1D15 interaction, activating Parkin‐mediated mitophagy. Long‐term high‐glucose exposure reduces Fis1 expression, inhibiting Parkin‐mediated mitophagy and triggering mitophagy switching from ...
Anqi Luo, Rui Wang, Jingwen Gong, Shuting Wang, Chuan Yun, Zongcun Chen, Yanan Jiang, Xiaoquan Liu, Haofu Dai, Haochen Liu, Yunsi Zheng   +10 more
wiley   +1 more source

The stabilized plaque: will the dream come true? [PDF]

European Heart Journal Supplements, 2001
Can we prevent myocardial infarction by stabilizing active plaques? Until now, our efforts at treating coronary disease have largely been aimed at reducing the development of atherosclerotic lesions recanalizing occluded coronary arteries and preventing complications of myocardial cell death, such as arrhythmias and heart failure.
openaire   +2 more sources

Bifurcation for a free boundary problem modeling a small arterial plaque [PDF]

arXiv, 2020
Atherosclerosis, hardening of the arteries, originates from small plaque in the arteries; it is a major cause of disability and premature death in the United States and worldwide. In this paper, we study the bifurcation of a highly nonlinear and highly coupled PDE model describing the growth of arterial plaque in the early stage of atherosclerosis. The
arxiv  

Noninvasive Assessment of β‐Secretase Activity Through Click Chemistry‐Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease

Advanced Science, EarlyView.
This study presents the NEV β‐secretase activity assay, a groundbreaking method for noninvasive evaluation of β‐secretase activity in Alzheimer's disease (AD) patients, enabling the generation of individualized β‐secretase activity profiles.
Hyoyong Kim, Junseok Lee, Audrey Qian, You‐Ren Ji, Ryan Zhang, Qixin Hu, Christopher Kazu Williams, Han‐Yu Chuang, Matthew D. Smalley, Yaya Xu, Liang Gao, Mary C. Mayo, Ting Zhang, Edwin M. Posadas, Zaldy S. Tan, Harry V. Vinters, Keith Vossel, Shino Magaki, Yazhen Zhu, Hsian‐Rong Tseng   +19 more
wiley   +1 more source

Ultrasonography of vulnerable atherosclerotic plaque in the carotid arteries: B-mode imaging

Journal of Ultrasonography, 2020
The most common type of stroke, i.e. ischemic stroke, is a great challenge for contemporary medicine as it poses both diagnostic and therapeutic difficulties.
Fedak Andrzej, Ciuk Katarzyna, Urbanik Andrzej   +2 more
doaj   +1 more source