Results 131 to 140 of about 162,485 (319)

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

Advanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang, Sirui Shen, Weixin Li, Mengyang Wang, Yudie Yang, Wu Luo, Xue Han, Zheng Xu, Julian Min, Xiaohong Long, Weijian Huang, Gaojun Wu, Yi Wang, Guang Liang   +13 more
wiley   +1 more source

Customized Hydrogel System for the Spatiotemporal Sequential Treatment of Periodontitis Propelled by ZEB1

Advanced Science, EarlyView.
Through elaborate design, a biodegradable scaffold with excellent mechanical properties and suitability is fabricated, providing spatial support for subsequent physiological activities. The prepared GA‐HBC‐LIC hydrogel possesses sequential antibacterial, antioxidant, anti‐inflammatory and immunomodulatory functions, offering a suitable chemical and ...
Jiafei Chen, Xiaoxu Guan, Lina Chen, Bingzhu Zheng, Feiyu Li, Chao Fang, Yike Fu, Xiang Li, Huiming Wang, Yi Zhou   +9 more
wiley   +1 more source

Countervailing Effects on Atherogenesis and Plaque Stability [PDF]

, 2009
Jeff Stevens, Steven R. Lentz
openalex   +1 more source

Is Serum Pregnancy-Associated Plasma Protein A Really a Potential Marker of Atherosclerotic Carotid Plaque Stability? [PDF]

, 2010
P. Heider, Nicole Pfäffle, Jaroslav Pelisek, Moritz Wildgruber, Holger Poppert, Martina Rudelius, Hans‐Henning Eckstein   +6 more
openalex   +1 more source

HDL‐Apolipoprotein in Alzheimer's Disease Revisited: From Periphery to CNS

AGING MEDICINE, EarlyView.
HDL‐apolipoproteins in the periphery and CNS contribute differently to Alzheimer's disease, influencing Aβ, p‐tau, brain structures, and cognition. Apolipoprotein AI and E, key HDL components in blood and CSF, may either protect against or accelerate AD, depending on their location. Created with BioGDP.com. ABSTRACT High‐density lipoprotein (HDL), as a
Yihong Huang, Jingyi Tang, Guohua Chen, Qiangqiang Wu, Yongfei Wang, Jianjun Chen, Simei Chen, Jun Liu, Xiaoyun Huang   +8 more
wiley   +1 more source

Risk Factors and Predictive Model for Ischemic Complications in Endovascular Treatment of Intracranial Aneurysms: Insights From a Large Patient Cohort

AGING MEDICINE, EarlyView.
Independent risk factors for ischemic complications in endovascular treatment of intracranial aneurysms were identified using machine learning methods, and the first prediction model for ischemic complications of all intracranial aneurysms was constructed. Moreover, the model showed a stable and excellent predictive efficacy.
Jianwen Jia, Zeping Jin, Mirzat Turhon, Yixin Lin, Xinjian Yang, Yang Wang, Yunpeng Liu   +6 more
wiley   +1 more source

e0211 Si Miao Yong An decoction promotes atherosclerotic plaque stability in vulnerable plaque rabbits [PDF]

, 2010
Lei Peng, J.-P. Zhang, Ming Li, Lain‐Jong Li, Yong Xu, G.-Y. Zhang, Can Yang, Y.-N. Zhou   +7 more
openalex   +1 more source

S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype

Frontiers in Cell and Developmental Biology
Introduction: Plaque rupture in atherosclerosis contributes to various acute cardiovascular events. As a new sulfide-containing donor, S-propargyl-cysteine (SPRC) has been reported to play a beneficial role in cardioprotection, potentially through its ...
Li Ping, Li Zhi-Ming, Zhang Bi-Shan, Zhu Lei, Yu Bo, Zhu Yi-Chun, Wang Ming-Jie   +6 more
doaj   +1 more source

DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice. [PDF]

J Clin Invest, 2023
Herman AB, Tsitsipatis D, Anerillas C, Mazan-Mamczarz K, Carr AE, Gregg JM, Wang M, Zhang J, Michel M, Henry-Smith CA, Harris SC, Munk R, Martindale JL, Piao Y, Fan J, Mattison JA, De S, Abdelmohsen K, Maul RW, Tanaka T, Moore AZ, DeMouth ME, Sidoli S, Ferrucci L, Liu Y, de Cabo R, Lakatta EG, Gorospe M.   +27 more
europepmc   +1 more source

Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease

Aggregate, EarlyView.
This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang, Chengyuan Qian, Yuncong Chen, Weijiang He, Zijian Guo   +4 more
wiley   +1 more source