Results 81 to 90 of about 986,615 (364)

An Effective Sanitizer for Fresh Produce Production: In Situ Plasma-Activated Water Treatment Inactivates Pathogenic Bacteria and Maintains the Quality of Cucurbit Fruit

Microbiology spectrum, 2023
Plasma-activated water (PAW) is an emerging sanitizer in the fresh food industry, where food safety must be achieved without a thermal kill step. Here, we demonstrate PAW generated in situ to be a competitive sanitizer technology, providing a significant
J. Rothwell, Jungmi Hong, S. J. Morrison, H. Vyas, Binbin Xia, A. Mai-Prochnow, R. McConchie, K. Phan-Thien, P. Cullen, D. Carter   +9 more
semanticscholar   +1 more source

Zero-dimensional chemical kinetic simulation of ROS/RNSin pulsed pulsed-discharge exposed water [PDF]

, 2019
The concentration variations of reactive oxygen/nitrogen species in water, such as H2O2, NO2 −, and NO3 − generated by pulsed-discharge plasma exposure, are calculated using reaction rates of chemical reactions and acid-base equilibrium in water.
GIVEN Martin, KAWAGUCHI Hideki, KAWAGUCHI Satoru, MACGREGOR Scott, SATOH Kohki, TAKAHASHI Kazuhiro, TIMOSHKIN Igor   +6 more
core   +2 more sources

On the Possibilities of Straightforward Characterization of Plasma Activated Water [PDF]

Plasma Chemistry and Plasma Processing, 2019
Plasma activated deionized water from a hot arc 150 W PAW synthesizer has been analyzed for nitrite, nitrate and peroxide densities. Observed nitrite and nitrate levels are impressive, reaching several millimoles per liter at few hundred kiloJoules per liter energy input.
Hoeben, Wilfred, van Ooij, Polo, Schram, Daan, Huiskamp, Tom, Pemen, Guus, Lukes, P.   +5 more
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Water Content and Thermoplastic Polyurethane Effects on Thrombosis Clotting [PDF]

, 2019
One of the main factors that can increase the chance of heart disease is unwanted blood clotting, or thrombosis. In addition, implantable biomaterials and/or medical devices are likely to trigger a series of adverse reactions that can lead to ...
Chou, Shih-Feng, Jackson, Monica, Neuenschwander, Pierre, Small, Madeline   +3 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Physical properties of natural and processed water using dielectric barrier and gliding arc discharge [PDF]

AIP Advances
In this study, we produced an atmospheric pressure dielectric barrier and a gliding arc plasma jet and explored their impact on various physical properties of different natural and processed waters. The investigation was carried out under varying volumes,
Roshan Chalise, Om Shree Rijal, Dipak Oli, Krishna Regmi, Sadip Nepal, Raju Khanal   +5 more
doaj   +1 more source

Plasma-Activated Water Promotes Wound Healing by Regulating Inflammatory Responses

Biophysica, 2021
Infection can hinder the process of wound healing, so it is important to begin antibacterial treatment quickly after a wound forms. Plasma activated water (PAW) can inactivate a variety of common wound infection bacteria.
Shuai Wang, Dehui Xu, Miao Qi, Bing Li, Sansan Peng, Qiaosong Li, Hao Zhang, Dingxin Liu   +7 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source