Results 41 to 50 of about 3,475,545 (379)
Background: Alzheimer's disease (AD) is the most common type of dementia and has no effective treatment to date. It is essential to develop a minimally invasive blood-based biomarker as a tool for screening the general population, but the efficacy ...
Bin Jiao+38 more
doaj +1 more source
Plasma amyloid beta (Aβ) and tau are emerging as accessible biomarkers for Alzheimer's disease (AD). However, many assays exist with variable test performances, highlighting the need for a comparative assessment to identify the most valid assays for ...
Ryan T. Muir+3 more
semanticscholar +1 more source
The importance of circulating tumor products as „liquid biopsies” in colorectal cancer [PDF]
Liquid biopsies represent an array of plasma analysis tests that are studied to evaluate and identify circulating tumor products, especially circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA).
Calborean, Veronica+6 more
core +4 more sources
High Plasma sTNF-R1 Level Is Related to Loss of Natural HIV Control in Long-Term Elite Controllers
Human immunodeficiency virus-1 (HIV-1) elite controllers are heterogeneous due to different immunovirological features. We aimed to identify plasma biomarkers associated with loss of spontaneous HIV-1 control in long-term elite controllers (HIV-LTECs ...
Daniel Sepúlveda-Crespo+14 more
doaj +1 more source
Associations of Alzheimer's-related plasma biomarkers with cognitive decline in Parkinson's disease
Parkinson’s disease (PD) is associated with cognitive decline through multiple mechanisms, including Alzheimer’s disease (AD) pathology and cortical Lewy body involvement. However, its underlying mechanisms remain unclear.
Y. Mizutani+8 more
semanticscholar +1 more source
Downregulation of plasma MiR-142-3p and MiR-26a-5p in patients with colorectal carcinoma [PDF]
Background: Colorectal cancer is one of the most commonly diagnosed cancers and cancer- related death worldwide. Identification of new specific biomarkers could be helpful to detection of this malignancy.
Asadi, J.+9 more
core +1 more source
Plasma gelsolin as a biomarker of inflammation [PDF]
The prognostic implications of declining plasma gelsolin levels have been documented after a diverse variety of acute insults. Because gelsolin concentrations fall prior to the development of complications, a pathophysiological role for gelsolin depletion has been postulated in delayed multiorgan failure.
openaire +3 more sources
Profiling of plasma biomarkers in the context of memory assessment in a tertiary memory clinic
Plasma biomarkers have shown promising performance in research cohorts in discriminating between different stages of Alzheimer’s disease (AD). Studies in clinical populations are necessary to provide insights on the clinical utility of plasma biomarkers ...
M. Bucci+10 more
semanticscholar +1 more source
Plasma total antioxidant capacity and peroxidation biomarkers in psoriasis [PDF]
Systemic biomarkers of oxidative stress can be relevant for assessment of psoriasis severity, for prediction of the outcome of therapy and of the development of comorbidities.
Cavaliere, Arturo+2 more
core +2 more sources
Plasma biomarkers for Alzheimer’s Disease in relation to neuropathology and cognitive change
Plasma biomarkers related to amyloid, tau, and neurodegeneration (ATN) show great promise for identifying these pathological features of Alzheimer’s Disease (AD) as shown by recent clinical studies and selected autopsy studies.
D. Smirnov+10 more
semanticscholar +1 more source