Results 11 to 20 of about 5,660,715 (321)
Plasma membrane integrity: implications for health and disease
BMC Biology, 2021 Plasma membrane integrity is essential for cellular homeostasis. In vivo, cells experience plasma membrane damage from a multitude of stressors in the extra- and intra-cellular environment.
Dustin A. Ammendolia +2 more
doaj +2 more sources
Nanoclustering as a dominant feature of plasma membrane organization [PDF]
Journal of Cell Science, 2014 Early studies have revealed that some mammalian plasma membrane proteins exist in small nanoclusters. The advent of super-resolution microscopy has corroborated and extended this picture, and led to the suggestion that many, if not most, membrane ...
Cambi, Alessandra +4 more
core +6 more sources
Structural basis of NINJ1-mediated plasma membrane rupture in cell death
Nature, 2023 Eukaryotic cells can undergo different forms of programmed cell death, many of which culminate in plasma membrane rupture as the defining terminal event^ 1 – 7 .
Morris Degen +16 more
semanticscholar +1 more source
Plasma membrane integrity in health and disease: significance and therapeutic potential
Cell Discovery, 2021 Maintenance of plasma membrane integrity is essential for normal cell viability and function. Thus, robust membrane repair mechanisms have evolved to counteract the eminent threat of a torn plasma membrane.
Catarina Dias, Jesper Nylandsted
semanticscholar +1 more source
NINJ1 mediates plasma membrane rupture during lytic cell death
Nature, 2020 Plasma membrane rupture (PMR) is the final cataclysmic event in lytic cell death. PMR releases intracellular molecules known as damage-associated molecular patterns (DAMPs) that propagate the inflammatory response1–3.
N. Kayagaki +26 more
semanticscholar +1 more source
A guide to plasma membrane solute carrier proteins
The FEBS Journal, 2020 This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily of transporter proteins and their roles in human cells. The SLC superfamily currently includes 458 transport proteins in 65 families that carry a wide variety ...
Mattia D. Pizzagalli +2 more
semanticscholar +1 more source
Nature Communications, 2020 Mycobacterium tuberculosis is a global health problem in part as a result of extensive cytotoxicity caused by the infection. Here, we show how M. tuberculosis causes caspase-1/NLRP3/gasdermin D-mediated pyroptosis of human monocytes and macrophages.
K. S. Beckwith +11 more
semanticscholar +1 more source
Nature Communications, 2020 Mixed lineage kinase domain-like (MLKL) is the terminal protein in the pro-inflammatory necroptotic cell death program. RIPK3-mediated phosphorylation is thought to initiate MLKL oligomerization, membrane translocation and membrane disruption, although ...
A. Samson +23 more
semanticscholar +1 more source
Evaluation of four different strategies to characterize plasma membrane proteins from banana roots [PDF]
, 2015 Plasma membrane proteins constitute a very important class of proteins. They are involved in the transmission of external signals to the interior of the cell and selective transport of water, nutrients and ions across the plasma membrane.
Carpentier, Sebastien C. +3 more
core +1 more source