Results 41 to 50 of about 5,660,715 (321)

Monoclonal antibody detection of plasma membrane cholesterol microdomains responsive to cholesterol trafficking

open access: yesJournal of Lipid Research, 2001
The hypothesis of lipid domains in cellular plasma membranes is well established. However, direct visualization of the domains has been difficult. Here we report direct visualization of plasma membrane cholesterol microdomains modulated by agents that ...
Howard S. Kruth   +5 more
doaj   +1 more source

Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1 [PDF]

open access: yes, 2006
The directional flow of the plant hormone auxin mediates multiple developmental processes, including patterning and tropisms. Apical and basal plasma membrane localization of AUXIN-RESISTANT1 (AUX1) and PIN-FORMED1 (PIN1) auxin transport components ...
Bennett, Malcolm   +4 more
core   +2 more sources

ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P2) and regulate its level at the plasma membrane

open access: yesNature Communications, 2017
ORP5 and ORP8, members of the oxysterol-binding protein (OSBP)-related proteins (ORP) family, are endoplasmic reticulum membrane proteins implicated in lipid trafficking.
R. Ghai   +8 more
semanticscholar   +1 more source

Regional distribution of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and protein mass in the ocular lens.

open access: yesJournal of Lipid Research, 1993
We have attempted to map the regional distribution of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) enzyme activity and protein mass along the radial axis of the ocular lens.
H Shi, R J Cenedella
doaj   +1 more source

Alpha-toxin induces programmed cell death of human T cells, B cells, and monocytes during USA300 infection. [PDF]

open access: yesPLoS ONE, 2012
This investigation examines the influence of alpha-toxin (Hla) during USA300 infection of human leukocytes. Survival of an USA300 isogenic deletion mutant of hla (USA300Δhla) in human blood was comparable to the parental wild-type strain and ...
Tyler K Nygaard   +10 more
doaj   +1 more source

High-resolution three-dimensional views of membrane-associated clathrin and cytoskeleton in critical-point-dried macrophages. [PDF]

open access: yes, 1983
We obtained high-resolution topographical information about the distribution of clathrin and cytoskeletal filaments on cytoplasmic membrane surfaces of macrophages spreading onto glass coverslips by both critical-point drying of broken-open cells and ...
Aggeler, J, Takemura, R, Werb, Z
core   +1 more source

Sphingolipid Organization in the Plasma Membrane and the Mechanisms That Influence It

open access: yesFront. Cell Dev. Biol., 2017
Sphingolipids are structural components in the plasma membranes of eukaryotic cells. Their metabolism produces bioactive signaling molecules that modulate fundamental cellular processes.
M. Kraft
semanticscholar   +1 more source

ABCC6 is a basolateral plasma membrane protein [PDF]

open access: yes, 2013
RATIONALE:: ABCC6 plays a crucial role in ectopic calcification; mutations of the gene cause pseudoxanthoma elasticum and general arterial calcification of infancy.
Apana, A.   +11 more
core   +4 more sources

Membrane order in the plasma membrane and endocytic recycling compartment. [PDF]

open access: yesPLoS ONE, 2017
The cholesterol content of membranes plays an important role in organizing membranes for signal transduction and protein trafficking as well as in modulating the biophysical properties of membranes.
David B Iaea, Frederick R Maxfield
doaj   +1 more source

An Overview of Cell Membrane Perforation and Resealing Mechanisms for Localized Drug Delivery

open access: yesPharmaceutics, 2022
Localized and reversible plasma membrane disruption is a promising technique employed for the targeted deposition of exogenous therapeutic compounds for the treatment of disease.
Stephanie He   +2 more
doaj   +1 more source

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