Results 251 to 260 of about 391,649 (370)

Obesity Biomarkers: Exploring Factors, Ramification, Machine Learning, and AI‐Unveiling Insights in Health Research

open access: yesMedComm, Volume 6, Issue 7, July 2025.
The graphical abstract emphasizes the complex nature of obesity, focusing on the interaction of behavioral, sociodemographic, genetic, and biomarker factors. It illustrates how lifestyle habits, demographics, and genetic predispositions influence obesity risk.
Ankita Awari   +8 more
wiley   +1 more source

Treatment Selection and Prioritization for the EJS ACT‐PD MAMS Trial Platform

open access: yesMovement Disorders, Volume 40, Issue 7, Page 1307-1317, July 2025.
Abstract Background There are currently no disease‐modifying therapies (DMTs) registered for Parkinson's disease (PD). The Edmond J. Safra Accelerating Clinical Trials in Parkinson Disease (EJS ACT‐PD) initiative will expedite clinical assessment of putative DMTs through a multi‐arm multistage (MAMS) trial, testing several treatments against a common ...
Cristina Gonzalez‐Robles   +117 more
wiley   +1 more source

Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS‐STING Pathway and Reverses Macrophage‐Like VSMC Phenotypes in Progeroid DNA‐Repair‐Deficient Ercc1Δ/− Mice

open access: yesAging Cell, Volume 24, Issue 7, July 2025.
Dietary restriction mitigates vascular aging in DNA‐repair‐deficient Ercc1Δ/− mice by reducing extracellular matrix remodeling, inflammation, oxidative stress, and switching of vascular smooth muscle cells to a macrophage‐like phenotype. Our findings suggest that the cGAS‐STING pathway plays a key role in vascular aging and that the benefits of dietary
S. J. M. Stefens   +14 more
wiley   +1 more source

Plasma renin activity and aldosterone concentration in children

open access: yesPediatric Research, 1974
M. Dillon, J. Ryness, T. Barratt
semanticscholar   +1 more source

The dark sides of the GPCR tree ‐ research progress on understudied GPCRs

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 14, Page 3109-3134, July 2025.
Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf   +10 more
wiley   +1 more source

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