Results 1 to 10 of about 1,449,118 (412)

Directed Expression of Tracheal Antimicrobial Peptide as a Treatment for Bovine-Associated Staphylococcus Aureus-Induced Mastitis in Mice

Frontiers in Veterinary Science, 2021
Bovine mastitis is perplexing the dairy industry since the initiation of intensive dairy farming, which has caused a reduction in the productivity of cows and an escalation in costs.
Zhipeng Zhang, Daijie Chen, Xubin Lu, Ruifeng Zhao, Zhi Chen, Zhi Chen, Mingxun Li, Tianle Xu, Tianle Xu, Yongjiang Mao, Yi Yang, Yi Yang, Zhangping Yang, Zhangping Yang   +13 more
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KPC-2-Producing Carbapenem-Resistant Klebsiella pneumoniae of the Uncommon ST29 Type Carrying OXA-926, a Novel Narrow-Spectrum OXA β-Lactamase

Frontiers in Microbiology, 2021
We isolated and characterized a carbapenem-resistant Klebsiella pneumoniae (CRKP) clinical strain from blood carrying a novel blaOXA gene, blaOXA–926, and belonging to ST29, an uncommon CRKP type. The strain, 130002, was genome sequenced using both short-
Lina Liu, Yu Feng, Li Wei, Yuling Xiao, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong   +7 more
doaj   +1 more source

Genetic Diversity and Characteristics of blaNDM-Positive Plasmids in Escherichia coli

Frontiers in Microbiology, 2021
New Delhi metallo-β-lactamases (NDMs), including at least 28 variants, are a rapidly emerging family of β-lactamases worldwide, with a variety of infections caused by NDM-positive strains usually associated with very poor prognosis and high mortality ...
Zhiren Zhang, Hengzhao Guo, Xiaodong Li, Wenting Li, Guang Yang, Wenjun Ni, Meixiao Zhan, Meixiao Zhan, Ligong Lu, Ligong Lu, Zhenlin Zhang, Xiaobin Li, Zhiling Zhou   +12 more
doaj   +1 more source

Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities

Nature Communications, 2021
Plasmid persistence in bacterial populations is strongly influenced by the fitness effects associated with plasmid carriage. However, plasmid fitness effects in wild-type bacterial hosts remain largely unexplored. In this study, we determined the fitness
Aida Alonso-del Valle, Ricardo León-Sampedro, J. Rodríguez-Beltrán, J. DelaFuente, M. Hernández-García, P. Ruiz-Garbajosa, R. Cantón, R. Peña-Miller, Á. San Millán   +8 more
semanticscholar   +1 more source

Bacteria have numerous distinctive groups of phage–plasmids with conserved phage and variable plasmid gene repertoires

Nucleic Acids Research, 2021
Plasmids and temperate phages are key contributors to bacterial evolution. They are usually regarded as very distinct. However, some elements, termed phage–plasmids, are known to be both plasmids and phages, e.g. P1, N15 or SSU5. The number, distribution,
E. Pfeifer, J. A. Moura de Sousa, M. Touchon, E. Rocha   +3 more
semanticscholar   +1 more source

Whole-Genome Sequence Analysis of an Extensively Drug-Resistant Salmonella enterica Serovar Agona Isolate from an Australian Silver Gull (Chroicocephalus novaehollandiae) Reveals the Acquisition of Multidrug Resistance Plasmids

mSphere, 2020
Although most of the approximately 94 million annual human cases of gastroenteritis due to Salmonella enterica resolve without medical intervention, antimicrobial therapy is recommended for patients with severe disease. Wild birds can be natural hosts of
Max L. Cummins, Martina Sanderson-Smith, Peter Newton, Nicholas Carlile, David N. Phalen, Kimberly Maute, Leigh G. Monahan, Bethany J. Hoye, Steven P. Djordjevic   +8 more
doaj   +1 more source

Species classification and novel plasmid identifications in Arcobacter cryaerophilus and Arcobacter cryaerophilus-like organisms

Frontiers in Microbiology, 2022
The Arcobacter is a globally emerging foodborne and zoonotic pathogen that can cause diarrhea in humans. It is relatively homogenous and clearly distinguishes the group from other Epsilonproteobacteria. Arcobacter cryaerophilus (A.
Guilan Zhou, Min Wang, Hairui Wang, Xiaoli Chen, Yixin Gu, Zhujun Shao, Jianzhong Zhang, Maojun Zhang   +7 more
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Genetic context of blaCTX–M–55 and qnrS1 genes in a foodborne Salmonella enterica serotype Saintpaul isolate from China

Frontiers in Microbiology, 2022
Salmonella enterica resistant to fluoroquinolones (FQs) and extended-spectrum cephalosporins (ESCs) has been deemed a high-priority pathogen by the WHO. Salmonella enterica serovar Saintpaul (S.
Lili Li, Lili Li, Rikke Heidemann Olsen, Jian Xiao, Hecheng Meng, Shifu Peng, Lei Shi   +6 more
doaj   +1 more source

Intracellular Delivery of DNA and Protein by a Novel Cell-Permeable Peptide Derived from DOT1L

Biomolecules, 2020
Cellular uptake and intracellular release efficiency of biomacromolecules is low because of hurdles in the cell membrane that result in limited access to intra-cellular targets with few functional effects.
Jingping Geng, Xiangli Guo, Lidan Wang, Richard Q. Nguyen, Fengqin Wang, Changbai Liu, Hu Wang   +6 more
doaj   +1 more source

Antimicrobial resistance of Salmonella Indiana from retail chickens in China and emergence of an mcr-1-harboring isolate with concurrent resistance to ciprofloxacin, cefotaxime, and colistin

Frontiers in Microbiology, 2022
Salmonella enterica serotype Indiana (S. Indiana) in Chinese poultry meat has aroused widespread concern because of its high prevalence and strong antimicrobial resistance. In consideration of the relationship in our previous study between S. Indiana and
Yujie Hu, Yujie Hu, Yingying He, Scott V. Nguyen, Scott V. Nguyen, Chang Liu, Chang Liu, Xin Gan, Wei Wang, Yinping Dong, Yinping Dong, Jin Xu, Fengqin Li, Séamus Fanning, Séamus Fanning, Séamus Fanning   +15 more
doaj   +1 more source