Results 111 to 120 of about 65,619 (298)

Chemical Adjustment of Fibrinolysis

Pharmaceuticals
Fibrinolysis is the process of the fibrin–platelet clot dissolution initiated after bleeding has been stopped. It is regulated by a cascade of proteolytic enzymes with plasmin at its core.
Alexey M. Shibeko, Ivan S. Ilin, Nadezhda A. Podoplelova, Vladimir B. Sulimov, Mikhail A. Panteleev   +4 more
doaj   +1 more source

Genetically conditioned interaction among microRNA‐155, alpha‐klotho, and intra‐renal RAS in male rats: Link to CKD progression

Physiological Reports
Incident chronic kidney disease (CKD) varies in populations with hypertension of similar severity. Proteinuria promotes CKD progression in part due to activation of plasminogen to plasmin in the podocytes, resulting in oxidative stress‐mediated injury ...
L. M. Harrison‐Bernard, L. Raij, R. X. Tian, E. A. Jaimes   +3 more
doaj   +1 more source

The Impact of the Fibrinolytic System on the Outcomes of Thrombolytic Therapy

Неотложная медицинская помощь
Thrombolysis is one of the effectively used methods for treating patients with acute vascular pathology. Despite the high technical success of this therapy, some problems of fibrinolytic treatment still remain unresolved.
R. E. Kalinin, E. A. Klimentova, I. A. Suchkov, A. A. Egorov, A. S. Pshennikov   +4 more
doaj   +1 more source

The evidence and the rationale for the use of honey as wound dressing [PDF]

, 2011
Although there are now several brands and types of honey wound-care products available as registered medical devices, there is little promotional advertising of honey products for wound care. The misconception that there is no evidence to support the use
Molan, Peter C.
core   +1 more source

Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices

Advanced Healthcare Materials, Volume 15, Issue 2, 14 January 2026.
Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco, Zhibing Zhang, Neil M. Eisenstein, Nigel Tai, Liam M. Grover   +4 more
wiley   +1 more source

Facts and Misfacts on D‐Dimer Testing. Consensus Guidance From the Italian Society on Thrombosis and Hemostasis (SISET)

American Journal of Hematology, Volume 101, Issue 1, Page 97-109, January 2026.
ABSTRACT D‐dimer defines degradation products derived from the proteolysis mediated by plasmin on cross‐linked fibrin. The evidence‐based use of D‐dimer in some conditions has been consolidated. Currently, however, there is an entrenched prescription of D‐dimer testing to screen otherwise healthy subjects that may induce prescribing physicians to start
Armando Tripodi, Walter Ageno, Luca Barcella, Antonio Coppola, Marcello Di Nisio, Massimo Franchini, Monia Marchetti, Rossella Marcucci, Marco Marietta, Pasquale Pignatelli, Domenico Prisco, Valerio De Stefano   +11 more
wiley   +1 more source

ALDH1A3 promotes invasion and metastasis in triple‐negative breast cancer by regulating the plasminogen activation pathway

Molecular Oncology
Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell marker that promotes metastasis. Triple‐negative breast cancer (TNBC) progression has been linked to ALDH1A3‐induced gene expression changes.
Alamelu G. Bharadwaj, Meghan E. McLean, Margaret L. Dahn, Hannah F. Cahill, Marie‐Claire D. Wasson, Raj Pranap Arun, Olivia L. Walker, Brianne M. Cruickshank, Wasundara Fernando, Jaganathan Venkatesh, Penelope J. Barnes, Gillian Bethune, Gregory Knapp, Lucy K. Helyer, Carman A. Giacomantonio, David M. Waisman, Paola Marcato   +16 more
doaj   +1 more source

Tranexamic Acid for Acute Upper Respiratory Tract Infection‐Associated Sore Throat Pain: A Randomized Controlled Trial

Journal of General and Family Medicine, Volume 27, Issue 1, January 2026.
ABSTRACT Background Tranexamic acid (TXA) is sometimes used to relieve sore throat discomfort from acute upper‐respiratory tract infection (URTI), but its clinical effect has not been demonstrated in robust randomized controlled trials. Methods The tranexamic acid for URTI study is a randomized double‐blinded clinical trial that was conducted between ...
Naoto Ishimaru, Toshio Shimokawa, Masataka Ono, Shimpei Mizuki, Yohei Kanzawa, Takahiro Nakajima   +5 more
wiley   +1 more source

Fibrinolytic states in a patient with congenital deficiency of alpha 2- plasmin inhibitor [PDF]

, 1980
N Aoki, Y Sakata, M Matsuda, Kei Tateno
openalex   +1 more source

Mortality Benefit of Tranexamic Acid for Hemorrhage With Concurrent Traumatic Brain Injury: Outcomes From a Prospective Cohort Study in a High‐Trauma, Prolonged Care Setting

World Journal of Surgery, Volume 50, Issue 1, Page 233-243, January 2026.
Early TXA administration (≤ 3 h) in concurrent hemorrhage and TBI was significantly associated with a 22% reduction in mortality at 7 days. TXA treatment was also associated with a significant 29% lower odds of organ failure and non‐significant 11% odds of good neurologic recovery.
Julia M. Dixon, Adane F. Wogu, Maria D. Rodriguez, Dale Barnhart, Rachel Patel, Hendrick J. Lategan, George Oosthuizen, Janette Verster, Shaheem de Vries, Craig Wylie, EpiC Study Site Collaborators, Elaine Erasmus, Steven G. Schauer, Nee‐Kofi Mould‐Millman   +13 more
wiley   +1 more source