Results 91 to 100 of about 39,772 (244)
Public Administration, EarlyView.ABSTRACT Artificial intelligence (AI) systems are increasingly being integrated into public sector decision‐making processes, with public managers relying on them to enhance their capabilities. As AI adoption becomes more widespread, discussions about its advantages and drawbacks intensify, alongside growing external expectations and pressures. However,
A. Paula Rodriguez Müller +2 more
wiley +1 more source
Atrophic Papulosis: A Systematic Review of Pediatric Cases
Pediatric Dermatology, EarlyView.ABSTRACT Background Atrophic papulosis is a rare occlusive vasculopathy that can present with isolated cutaneous disease or with systemic involvement. Pediatric cases are uncommon, and existing reports are heterogeneous, limiting understanding of disease patterns, timing of organ involvement, and outcomes.
Ou Jia Emilie Wang +4 more
wiley +1 more source
Periodontology 2000, EarlyView.AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer +4 more
wiley +1 more source
Heat Inactivation of Bovine Plasmin.
, 1998 The thermal behaviour of the protease plasmin was studied in the absence and presence of milk components. A global unfolding of the isolated plasmin occurred at 50-55oC, but secondary structure of plasmin increased with increasing temperature, possibly ...
Jongh, H.H.J., de +2 more
core +1 more source
Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.Chemical peptide synthesis allows the generation of structurally highly diverse compounds suited for ligand development, but current methods in parallel peptide synthesis limit the achievable library size to a few thousand. A strategy is presented based on combinatorial pairing of short peptides via disulfide linkage that enables the generation and ...
Anne Zarda +5 more
wiley +2 more sources
Transfusion Medicine, EarlyView.Abstract Objectives To highlight tranexamic acid (TXA) as ‘just one thing’ that every hospital could implement to reduce surgical bleeding and blood transfusions. Background TXA is a low‐cost antifibrinolytic agent that inhibits the breakdown of fibrin blood clots. Developed in Japan in the 1960s, it has been shown to reduce surgical bleeding.
Ian Roberts, Katharine Ker
wiley +1 more source
Biochemistry and Biophysics Reports, 2017 Background: Protease-activated receptor-1 (PAR-1) potentiates diabetic nephropathy (DN) as evident from reduced kidney injury in diabetic PAR-1 deficient mice. Although thrombin is the prototypical PAR-1 agonist, anticoagulant treatment does not limit DN
Maaike Waasdorp +2 more
doaj +1 more source
INACTIVATION OF ACTH BY HUMAN PLASMIN SYSTEM AND EFFECT OF PLASMIN INHIBITORS
Endocrinologia Japonica, 1964 The inactivation of ACTH by human plasma or euglobulin fraction activated by streptokinase in vitro was studied.The assay of ACTH was carried out by the method of adrenal ascorbic acid depletion of non-hypophysectomized rat treated withprednisolone 4 hrs.
YAMAMURA, YUICHI +5 more
openaire +3 more sources
Warburg redefined: Metabolites, mitochondria and macrophages in immune regulation
The Journal of Physiology, EarlyView.Abstract figure legend Following pro‐inflammatory stimulation, macrophages undergo Warburg‐like metabolic rewiring that extends more than increased glycolysis. The non‐canonical functions of glycolytic enzymes and lactate accumulation control macrophage immune responses through multiple signalling pathways (a).
Yukun Min +2 more
wiley +1 more source
Laminin Degradation by Plasmin Regulates Long-Term Potentiation
, 2000 Plasmin is converted from its zymogen plasminogen by tissue type or urokinase type plasminogen activator (PA) and degrades many components of the extracellular matrix (ECM).
Kazuho Abe +3 more
core +1 more source