Results 91 to 100 of about 30,314 (207)
Recombinant chymase inhibits fibrinolysis induced by endogenous plasmin in clotted human blood
Frontiers in ImmunologyBackgroundOur group recently reported that chymase, a serine protease synthetized and released by mast cells, plays a pivotal role in thrombi stabilization in murine deep vein thrombosis (DVT) models, by interfering with the fibrinolytic properties of ...
Laurence Vincent +8 more
doaj +1 more source
Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases
British Journal of Pharmacology, Volume 183, Issue 15, Page 4111-4125, August 2026.Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden +3 more
wiley +1 more source
Garadacimab for the long‐term prophylaxis of hereditary angioedema
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page e1034-e1044, August 2026.Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün +5 more
wiley +1 more source
Garadacimab zur Langzeitprophylaxe bei hereditärem Angioödem
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page 1034-1046, August 2026.Zusammenfassung Das hereditäre Angioödem (Hereditary angioedema, HAE), eine seltene und belastende Erkrankung, die durch rezidivierende und spontane Gewebeschwellungsattacken gekennzeichnet ist, weist einen hohen ungedeckten therapeutischen Bedarf auf, da Patienten unter aktuellen prophylaktischen Behandlungen eine unzureichende Krankheitskontrolle ...
Emel Aygören‐Pürsün +5 more
wiley +1 more source
International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 721-731, August 2026.ABSTRACT Introduction Investigator‐led research and quality improvement initiatives have led to important improvements in the diagnostic assessment of platelet function disorders (PFD). Methods Personal reflections were used to summarize our contributions to knowledge on PFD diagnostic assessment, pathogenesis, and bleeding risks.
Catherine P. M. Hayward
wiley +1 more source
Journal of Food Process Engineering, Volume 49, Issue 8, August 2026.The retention of lactoferrin lactoperoxidase, and lysozyme in milk concentrated by ultrafiltration (UF) before cheesemaking and on cheese properties was studied. Cheese made with concentrated milk retained 17% more LF than the control. No effect on cheese properties was observed. UF could be an additional tool to enhance cheese bioactivity.
Marie‐Claude Gentès +3 more
wiley +1 more source
mBioStaphylococcus epidermidis, a common commensal bacterium, is a leading cause of nosocomial catheter-associated bloodstream infections. S. epidermidis sequence type 2 (ST2) is specifically recognized globally for causing invasive disease.
Amy A. Gomez +10 more
doaj +1 more source
Activation of Trypsinogen by Plasmin.
Experimental Biology and Medicine, 1967 M V, Goldblat, D L, Kline, J H, Milstone
openaire +2 more sources
Investigations on Plasmin. I. On the Proteolytic Activity of Plasmin. [PDF]
Acta Chemica Scandinavica, 1949 Gunnar Lundblad +3 more
openaire +1 more source