Results 71 to 80 of about 39,772 (244)
Studies on interactions of α2 plasmin inhibitor with plasmin
Blood & Vessel, 1980 When plasmin was mixed with α2M or α2PI, plasmin was inhibited faster by α2PI than by α2M. When plasma was mixed with UK and fluorescamine-labeled casein (f-casein), hydrolysis of f-casein was observed 10min after incubation started, and increased significantly after 20min incubation.
TAKADA, Yumiko, TAKADA, Akikazu
openaire +2 more sources
Peripheral targets for neuropathic pain
British Journal of Pharmacology, EarlyView.Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour +3 more
wiley +1 more source
The plasmin-antiplasmin system: structural and functional aspects [PDF]
, 2018 The plasmin-antiplasmin system plays a key role in blood coagulation and fibrinolysis. Plasmin and α2-antiplasmin are primarily responsible for a controlled and regulated dissolution of the fibrin polymers into soluble fragments. However, besides plasmin(
Gerber, Simon, Schaller, Johann
core
British Journal of Pharmacology, EarlyView.As a metabolically versatile organ, the heart is capable of generating energy from a wide range of substrates. Although fatty acid and glucose metabolism in the heart have been extensively studied, the contribution of amino acid metabolism to cardiac physiology and disease is gaining increasing attention.
Tayyiba Azam +6 more
wiley +1 more source
BioTechniques, 1996 MatrigelTM, a basement membrane (BM) extract of the Engelbreth-Holm-Swarm (EHS) sarcoma, used in tumor invasion assays, was found to contain plasminogen.
A.R. Farina +6 more
doaj +1 more source
, 2018 All cells in the model (A) express the same level of uPAR (the uPAR concentration in the cells is indicated by the red color) at initialization of a simulation.
Joao Carvalho (5487974) +6 more
core +1 more source
Cancer Science, EarlyView.Lung cancer brain metastasis is shaped by dynamic crosstalk among tumor cells, the blood–brain barrier, glial and immune cells, neurons, and metabolic niches. This review integrates these mechanisms with therapeutic resistance, translational models, CNS delivery, and multidisciplinary treatment strategies.
Jun Yang +6 more
wiley +1 more source
Thrombosis and Thrombolysis: Emphasis on Hemophilia and Effect of Clot Dissolution with Plasmin
, 2006 The purpose of this research was to understand the mechanisms in which blood clots form and are degraded. The research studies examined the role of an endogenous protease, plasmin, which is found in all vertebrates, and the optimal doses of plasmin ...
Landskroner, Kyle Alan
core
BMJ Open, 2019 ObjectivesPre-eclampsia (PE) is characterised by renal glomerular endotheliosis and injury to the glomerular filtration barrier with proteinuria. Patients with PE display aberrant filtration of the plasma proenzyme plasminogen which is activated, in the ...
Lise H Nielsen +6 more
doaj +1 more source
Advances in Analysis of Milk Proteases Activity at Surfaces and in a Volume by Acoustic Methods
Sensors, 2020 This review is focused on the application of surface and volume-sensitive acoustic methods for the detection of milk proteases such as trypsin and plasmin. While trypsin is an important protein of human milk, plasmin is a protease that plays an important
Mark Dizon, Marek Tatarko, Tibor Hianik
doaj +1 more source