Results 51 to 60 of about 38,888 (195)

Stability of the octameric structure affects plasminogen-binding capacity of streptococcal enolase. [PDF]

PLoS ONE, 2015
Group A Streptococcus (GAS) is a human pathogen that has the potential to cause invasive disease by binding and activating human plasmin(ogen). Streptococcal surface enolase (SEN) is an octameric α-enolase that is localized at the GAS cell surface.
Amanda J Cork, Daniel J Ericsson, Ruby H P Law, Lachlan W Casey, Eugene Valkov, Carlo Bertozzi, Anna Stamp, Blagojce Jovcevski, J Andrew Aquilina, James C Whisstock, Mark J Walker, Bostjan Kobe   +11 more
doaj   +1 more source

Changes in levels of urokinase receptor and other components of fibrinolytic system in brain tissues in urokinase gene-knockout mice with B16/F10 melanoma growing together with chronic neurogenic pain

Исследования и практика в медицине, 2022
Purpose of the study. An analysis of the changes in components of the urokinase system in the brain of urokinase gene-knockout mice (uPA-/-) with B16/F10 melanoma growing alone and together with chronic neurogenic pain (CNP).Materials and methods.
E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, N. D. Cheryarina, E. I. Surikova, I. V. Neskubina, Yu. A. Pogorelova, L. A. Nemashkalova   +7 more
doaj   +1 more source

Plants, people and their shared heritage: A comparative medicinal and wild food ethnobotany of Albanians, Greeks and Aromanians living in the Gjirokaster area, southern Albania

PLANTS, PEOPLE, PLANET, EarlyView.
Traditional knowledge about wild plants connects people to nature and sustains both cultural identity and biodiversity. This study explores how cultural exchange among Albanians, Greeks and Aromanians in southern Albania shapes the use and naming of medicinal and food plants.
Evanthia Dina, Ani Bajrami, Mousaab Alrhmoun, Naji Sulaiman, Konstantinos Ntinas, Marjol Meço, Bledar Pulaj, Nektarios Aligiannis, Avni Hajdari, Andrea Pieroni   +9 more
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Role of defensins in immunothrombosis

Rheumatology &Autoimmunity, EarlyView.
Defensins are important proteins that link the immune system and blood clotting, playing a key role in immunothrombosis. α‐defensins mainly come from neutrophils, while β‐defensins are produced by epithelial cells and platelets. These proteins help form blood clots in several ways: they slow down clot breakdown (fibrinolysis), activate platelets, and ...
Yuebing Wang, Guijuan Guo, Xiangjun Liu, Xiaoyu Chen, Wenqiong Wang, Patapong Towiwat, Ru Li, Chun Li   +7 more
wiley   +1 more source

Bi-KTI inhibits plasmin.

, 2013
(A) Bi-KTI-mediated plasmin inhibition assay. The number indicates the time (in min) that fibrin was incubated with plasmin or both plasmin and Bi-KTI. The FDPs are shown. (B) The antifibrinolytic activity of Bi-KTI.
Hyung Joo Yoon (249514), Hung Dae Sohn (249518), Yuling Qiu (332854), Kwang Sik Lee (249513), Hu Wan (290689), Young Moo Choo (249512), Mi Ri Sohn (249515), Byung Rae Jin (249519)   +7 more
core   +1 more source

Using antifibrinolytics to tackle neuroinflammation

Neural Regeneration Research, 2020
Plasmin is generally known as a promotor of inflammation. Recent advancement suggests that it has a complex role as immunity modulator. Pharmacological inhibition of plasmin production and activity has been proven to improve neurological outcomes in ...
Stanimir Atsev, Nikola Tomov
doaj   +1 more source

Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang, Chen Zhang, Jia‐Ni Chen, Fu‐Ying Cheng, Yi‐Zhang Wang, Shi‐Rui Xue, Huan Wang, De‐Hui Wang, Xi‐Cai Sun, Li Hu   +9 more
wiley   +1 more source

Changes of Microbial and Component Composition of Giraffe Milk During Mid‐ to Late Lactation

Zoo Biology, EarlyView.
Giraffe milk – graphical abstract text, Giraffe: late lactation milk, Involution at approximately 15 months of lactation, Content of saccharides and fat decrease, Protein content increases, Content of minerals increase, Microbiological quality high ABSTRACT The proximate, mineral and microbiological composition of milk from five giraffes from mid ...
G. Osthoff, C. J Hugo, S Van der Merwe, A Hugo, F Deacon   +4 more
wiley   +1 more source

Plasmin degrades C3a.

, 2013
(A) C3a was completely degraded by plasmin; plasminogen had a weak degrading effect. S. aureus was incubated with C3a in the presence of plasmin (PLG+SAK) (lane 4) or plasminogen alone (lane 6). The supernatants were analyzed by SDS-PAGE and Western blot
Tina K. Koch (303277), Jean van den Elsen (268290), Peter Kraiczy (36173), Christine Skerka (105424), Michael Reuter (268288), Sascha Böhm (303280), Peter F. Zipfel (105431), Diana Barthel (303279)   +7 more
core   +1 more source