Results 61 to 70 of about 39,772 (244)
Changes of Microbial and Component Composition of Giraffe Milk During Mid‐ to Late Lactation
Zoo Biology, EarlyView.Giraffe milk – graphical abstract text, Giraffe: late lactation milk, Involution at approximately 15 months of lactation, Content of saccharides and fat decrease, Protein content increases, Content of minerals increase, Microbiological quality high ABSTRACT The proximate, mineral and microbiological composition of milk from five giraffes from mid ...
G. Osthoff +4 more
wiley +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective To demonstrate the presence of peritoneal fluid (PF)‐derived small extracellular vesicles (sEVs) in endometriosis and control samples, to characterise their protein content and to define endometriosis‐specific biomarkers within the sEV proteome. Design Case–control experimental study. Setting Academic endometriosis centre.
Hannah M. Nazri +8 more
wiley +1 more source
Using antifibrinolytics to tackle neuroinflammation
Neural Regeneration Research, 2020 Plasmin is generally known as a promotor of inflammation. Recent advancement suggests that it has a complex role as immunity modulator. Pharmacological inhibition of plasmin production and activity has been proven to improve neurological outcomes in ...
Stanimir Atsev, Nikola Tomov
doaj +1 more source
Evolutionary Mechanisms of Coagulation Factors in Cetaceans During Aquatic Adaptation
Integrative Zoology, EarlyView.Compared with Bos taurus, T. truncatus showed shorter prothrombin time and thrombin time but prolonged activated partial thromboplastin time, indicating pathway‐specific remodeling of coagulation. Evolutionary analyses identified 18 positively selected genes and accelerated F11 evolution, while functional assays revealed increased coagulation factor ...
Wenjun Lv +4 more
wiley +1 more source
Fibrinogenolytic and fibrinolytic activity of cell-associated plasmin.
, 1993 Binding of plasmin(ogen) to rat C6 glioma cells is saturable and kringle-domain dependent. This interaction was studied as a model of plasmin(ogen) receptor interactions in nucleated mammalian cells.
S L Gonias, J Vasudevan, J E Humphries
core +1 more source
Pulmonary Embolism—A Century of Progress
ANZ Journal of Surgery, EarlyView.Reviews a century of progress in the diagnosis, prevention, and management of pulmonary embolism; from the first successful surgical embolectomy in 1924 to advanced imaging, pharmacological thromboprophylaxis, and treatment. In the 21st century, advances include catheter‐directed thrombolysis or mechanical thrombectomy under decision‐making guidance of
D. A. Watters
wiley +1 more source
Effect of lactosylation on plasmin-induced hydrolysis of β-casein.
, 2014 The inhibition of the plasmin-induced hydrolysis of β-casein was explored by decreasing β-casein availability through lactosylation. As plasmin hydrolyses proteins on the carboxyl site of lysine and arginine residues, with a preference for lysine, the ...
Bhatt, H. +3 more
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British Journal of Pharmacology, EarlyView.Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley +1 more source
The effect of plasmin on platelet function
, 1996 There is controversy in the literature regarding the effects of plasmin on human platelets, We have studied the effects of plasmin on platelet glycoproteins, aggregation, shape change and secretion and found them to be dependent on experimental ...
Vermylen, Jozef +3 more
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Effects of Plasmin on von Willebrand Factor and Platelets: A Narrative Review
TH Open, 2018 Plasmin is the major fibrinolytic protease responsible for dissolving thrombi by cleavage of its primary substrate fibrin. In addition, emerging evidence points to other roles of plasmin: (1) as a back-up for ADAMTS13 in proteolysis of ultra-large von ...
Lisa N. van der Vorm +3 more
doaj +1 more source