Results 81 to 90 of about 38,888 (195)
Tranexamic Acid Improves Memory and Learning Abilities in Aging Mice
Journal of Experimental Pharmacology, 2020 Keiichi Hiramoto,1 Yurika Yamate,1 Kazunari Matsuda,2 Daijiro Sugiyama,2 Yasutaka Iizuka2 1Department of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka, Mie 513-8670, Japan; 2R&D Department, Daiichi Sankyo Healthcare Co., LTD ...
Hiramoto K +4 more
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International Journal of Dermatology, EarlyView.Merlin CP‐GEP integrates mechanistic insights into a clinically actionable assay to predict SLN metastasis risk and inform personalized management of cutaneous melanoma. ABSTRACT The recent inclusion of the Merlin clinicopathologic–gene expression profile (CP‐GEP) assay in the National Comprehensive Cancer Network (NCCN) Melanoma Guidelines represents ...
Frank Z. Jing, Alexander Meves
wiley +1 more source
Plasmin activity in pressurized milk
, 2003 The effects of pressure (up to 400 MPa), applied at room temperature, on native proteinase activity of milk were investigated by means of plasmin activity, plasmin-derived activity after plasminogen activation and their distribution in different milk ...
Recio, Isidra +3 more
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International Journal of Laboratory Hematology, EarlyView.ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic +3 more
wiley +1 more source
The effect of plasmin on platelet function
, 1996 There is controversy in the literature regarding the effects of plasmin on human platelets, We have studied the effects of plasmin on platelet glycoproteins, aggregation, shape change and secretion and found them to be dependent on experimental ...
Vermylen, Jozef +3 more
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Truncation of ADAMTS13 by Plasmin Enhances Its Activity in Plasma [PDF]
, 2018 ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) cleaves von Willebrand Factor (VWF) multimers to control their thrombogenicity. The fibrinolytic enzyme plasmin can cleave VWF in a similar manner.
Tielens, Aloysius G M +18 more
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Biochemistry and Biophysics Reports, 2017 Background: Protease-activated receptor-1 (PAR-1) potentiates diabetic nephropathy (DN) as evident from reduced kidney injury in diabetic PAR-1 deficient mice. Although thrombin is the prototypical PAR-1 agonist, anticoagulant treatment does not limit DN
Maaike Waasdorp +2 more
doaj +1 more source
Coagulation and Fibrinolysis in Normal Pregnancy and Complicated Pregnancy
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Pregnancy induces significant physiological changes in the hemostatic system, leading to a hypercoagulable state to prevent postpartum hemorrhage. These adaptations involve alterations in coagulation and fibrinolysis, which can be further modified in complicated pregnancies such as gestational diabetes mellitus (GDM) and ...
Yang Su +6 more
wiley +1 more source
Genetic Susceptibility to Periodontitis
Journal of Periodontal Research, EarlyView.Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley +1 more source
Fibrinogenolytic and fibrinolytic activity of cell-associated plasmin.
, 1993 Binding of plasmin(ogen) to rat C6 glioma cells is saturable and kringle-domain dependent. This interaction was studied as a model of plasmin(ogen) receptor interactions in nucleated mammalian cells.
S L Gonias, J Vasudevan, J E Humphries
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