Results 81 to 90 of about 39,772 (244)
Haemophilia, EarlyView.ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini +4 more
wiley +1 more source
, 2010 Plasmin is a direct-acting thrombolytic agent with a striking hemostatic safety advantage over plasminogen activators in animal models of thrombolysis and bleeding.
Victor J. Marder +4 more
core +1 more source
Urinary pro-thrombotic, anti-thrombotic, and fibrinolytic molecules as biomarkers of lupus nephritis
Arthritis Research & Therapy, 2019 Objective This study evaluates the utility of urinary pro-thrombotic molecules such as tissue factor (TF), anti-thrombotic molecules such as tissue factor pathway inhibitor (TFPI), and fibrinolytic molecules such as plasmin and d-dimer as biomarkers of ...
Ling Qin +10 more
doaj +1 more source
International Journal of Dental Hygiene, EarlyView.ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur +6 more
wiley +1 more source
International Journal of Dermatology, EarlyView.Merlin CP‐GEP integrates mechanistic insights into a clinically actionable assay to predict SLN metastasis risk and inform personalized management of cutaneous melanoma. ABSTRACT The recent inclusion of the Merlin clinicopathologic–gene expression profile (CP‐GEP) assay in the National Comprehensive Cancer Network (NCCN) Melanoma Guidelines represents ...
Frank Z. Jing, Alexander Meves
wiley +1 more source
Plasmin activity in the conditioned media.
, 2012 (A) Western blot analysis for detection of plasmin(ogen) with a monoclonal anti-human plasminogen antibody, in conditioned medium obtained from the VG and N samples of 2 representative patients (Pn and Pg: purified human plasmin, 0.25 µg per well, and ...
Stéphane Loyau (134545) +9 more
core +1 more source
A chromatographic approach to understanding the plasmin-plasminogen system in acid whey
, 2020 An affinity chromatographic approach was used to investigate the plasmin activity observed in bovine acid whey. Plasminogen-removal gel with tranexamic acid as a ligand was used for selective binding of plasminogen and plasmin through their kringle ...
Czárán, Tamás László +2 more
core +1 more source
Tranexamic Acid Improves Memory and Learning Abilities in Aging Mice
Journal of Experimental Pharmacology, 2020 Keiichi Hiramoto,1 Yurika Yamate,1 Kazunari Matsuda,2 Daijiro Sugiyama,2 Yasutaka Iizuka2 1Department of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka, Mie 513-8670, Japan; 2R&D Department, Daiichi Sankyo Healthcare Co., LTD ...
Hiramoto K +4 more
doaj
Genetic Susceptibility to Periodontitis
Journal of Periodontal Research, EarlyView.Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley +1 more source
Plasmin-Cleavable Nanoparticles for On-Demand Release of Morphogens in Vascularized Osteogenesis
, 2019 The objective of this work was to engineer self-assembled nanoparticles (NPs) for on-demand release of bone morphogenetic protein-2 (BMP2) and vascular endothelial growth factor (VEGF) in response to enzymes secreted by the migrating human mesenchymal ...
Seyedsina Moeinzadeh (390901) +11 more
core +1 more source