Results 1 to 10 of about 190,587 (365)

Plasminogen Assay [PDF]

open access: bronzeClinical Chemistry, 1968
Abstract An indirect caseinolytic assay for plasminogen utilizing acid-treated plasma or serum and optimal concentrations of streptokinase is described. A linear response to increasing plasma or serum concentrations was observed. An acid-treated plasma or serum sample is preferable to euglobulin.
William R. Swaim
openalex   +3 more sources

Plasminogen deficiency [PDF]

open access: yesHaemophilia, 2008
Summary.  Plasminogen deficiency has emerged as a well‐recognized disorder in which reduced levels of plasminogen lead to the development of pseudo membranes on mucosal surfaces, with subsequent end‐organ damage of the affected tissue. Ligneous conjunctivitis is the most recognizable, well‐documented, and common presentation of the clinical syndromes ...
Mauro Tognon
exaly   +4 more sources

Plasminogen Activator Inhibitor Type‐1 as a Regulator of Fibrosis

open access: yesJournal of Cellular Biochemistry, 2018
Fibrosis is known as a frequent and irreversible pathological condition which is associated with organ failure. Tissue fibrosis is a central process in a variety of chronic progressive diseases such as diabetes, hypertension, and persistent inflammation.
Maryam Boshtam, Rui Dinis, Hamed Mirzaei
exaly   +2 more sources

Plasminogen: an enigmatic zymogen.

open access: yesBlood, 2021
Plasminogen is an abundant plasma protein that exists in various zymogenic forms. Plasmin, the proteolytically active form of plasminogen, is known for its essential role in fibrinolysis.
Charithani B. Keragala   +1 more
semanticscholar   +4 more sources

Plasminogen activator inhibitors. [PDF]

open access: yesBlood, 1987
Chemicals/CAS: fibrin, 9001-31-4; plasminogen activator inhibitor, 105844-41-5; plasminogen activator, 9039-53-6; Carrier Proteins; Glycoproteins; Plasminogen Activators, EC 3.4.21.-; Plasminogen Inactivators; Protease Inhibitors; protease ...
E. Sprengers, C. Kluft
semanticscholar   +5 more sources

Plasminogen receptors and their role in the pathogenesis of inflammatory, autoimmune and malignant disease

open access: yesJournal of Thrombosis and Haemostasis, 2013
Summary.  Plasminogen is the proenzyme of plasmin, the key protease of the fibrinolytic system, but its role is not limited to fibrinolysis regulation. Plasminogen binds not only to fibrin, but also to different receptors on cell surfaces, including the ...
A. Godier, B. Hunt, B. Hunt
exaly   +2 more sources

Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial

open access: yesNature Network Boston, 2021
Early increase of soluble urokinase plasminogen activator receptor (suPAR) serum levels is indicative of increased risk of progression of coronavirus disease 2019 (COVID-19) to respiratory failure.
E. Kyriazopoulou   +63 more
semanticscholar   +1 more source

A Narrative Review on Plasminogen Activator Inhibitor-1 and Its (Patho)Physiological Role: To Target or Not to Target?

open access: yesInternational Journal of Molecular Sciences, 2021
Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of plasminogen activators (PAs) and is therefore an important inhibitor of the plasminogen/plasmin system.
M. Sillen, P. Declerck
semanticscholar   +1 more source

Phosphorylation of human plasminogen activators and plasminogen [PDF]

open access: yesFEBS Letters, 1995
Plasminogen (PG), urokinase‐type plasminogen activator (u‐PA) and tissue‐type PA (t‐PA) are the main molecules involved in fibrinolysis and in many other physiological and pathological processes. In the present study we report that human t‐PA, purified from human melanoma cells, and PG, purified from human plasma, both contain P‐Tyr residues, as ...
BARLATI, Sergio   +4 more
openaire   +4 more sources

A multifunctional enolase mediates cytoadhesion and interaction with host plasminogen and fibronectin in Mycoplasma hyorhinis

open access: yesVeterinary Research, 2022
Mycoplasma hyorhinis may cause systemic inflammation of pigs, typically polyserositis and arthritis, and is also associated with several types of human cancer. However, the pathogenesis of M.
Jia Wang   +12 more
doaj   +1 more source

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