Results 1 to 10 of about 207,129 (257)

Diagnostic Ultrasound Induced Inertial Cavitation To Non-Invasively Restore Coronary And Microvascular Flow In Acute Myocardial Infarction [PDF]

open access: yes, 2013
Ultrasound induced cavitation has been explored as a method of dissolving intravascular and microvascular thrombi in acute myocardial infarction. The purpose of this study was to determine the type of cavitation required for success, and whether longer ...
Everbach, E. Carr   +11 more
core   +28 more sources

Plasminogen deficiency [PDF]

open access: yesHaemophilia, 2008
Summary.  Plasminogen deficiency has emerged as a well‐recognized disorder in which reduced levels of plasminogen lead to the development of pseudo membranes on mucosal surfaces, with subsequent end‐organ damage of the affected tissue. Ligneous conjunctivitis is the most recognizable, well‐documented, and common presentation of the clinical syndromes ...
R, Mehta, A D, Shapiro
openaire   +2 more sources

Phosphorylation of human plasminogen activators and plasminogen [PDF]

open access: yesFEBS Letters, 1995
Plasminogen (PG), urokinase‐type plasminogen activator (u‐PA) and tissue‐type PA (t‐PA) are the main molecules involved in fibrinolysis and in many other physiological and pathological processes. In the present study we report that human t‐PA, purified from human melanoma cells, and PG, purified from human plasma, both contain P‐Tyr residues, as ...
BARLATI, Sergio   +4 more
openaire   +3 more sources

Plasminogen–receptor KT: plasminogen activation and beyond [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2017
The cell surface orchestrates plasminogen activation through the concomitant binding of plasminogen and plasminogen activators to specific receptors. In this issue, Miles and colleagues describe their detailed phenotypic characterization of mice deficient in Plg-RKT, a key plasminogen receptor expressed in numerous tissues, but highly expressed by ...
M J, Flick, T H, Bugge
openaire   +2 more sources

Synthesis of human plasminogen by the liver [PDF]

open access: yes, 1980
Genetic types of plasminogen were determined from a donor and a recipient before and after hepatic homotransplantation. Examination of the plasminogen types demonstrated that the liver is the principal site of synthesis of human plasminogen.
Alper, CA   +5 more
core   +1 more source

Plasminogen Receptors and Fibrinolysis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
The ability of cells to promote plasminogen activation on their surfaces is now well recognized, and several distinct cell surface proteins have been demonstrated to function as plasminogen receptors. Here, we review studies demonstrating that plasminogen bound to cells, in addition to plasminogen directly bound to fibrin, plays a major role in ...
Lindsey A. Miles   +5 more
openaire   +3 more sources

Effects of stage of lactation and time of year on plasmin-derived proteolytic activity in bovine milk in New Zealand [PDF]

open access: yes, 2002
The objective of this study was to determine the effects of stage of lactation (SOL) and time of year on plasmin-derived proteolytic activity in the milk of pasture-fed dairy cows in New Zealand. Four herds of 20 Friesian cows were used, one herd calving
Auldist, Martin J.   +4 more
core   +2 more sources

Plasminogen activator inhibitors [PDF]

open access: yesBlood, 1987
Chemicals/CAS: fibrin, 9001-31-4; plasminogen activator inhibitor, 105844-41-5; plasminogen activator, 9039-53-6; Carrier Proteins; Glycoproteins; Plasminogen Activators, EC 3.4.21.-; Plasminogen Inactivators; Protease Inhibitors; protease ...
Sprengers, E.D., Kluft, C.
openaire   +4 more sources

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

open access: yes, 2017
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila   +5 more
core   +2 more sources

Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA [PDF]

open access: yes, 2009
HGF (hepatocyte growth factor) is a pleiotropic cytokine homologous to the serine protease zymogen plasminogen that requires canonical proteolytic cleavage to gain functional activity.
Andrew M. Schumacher   +47 more
core   +3 more sources

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