Results 1 to 10 of about 241,553 (351)

Diagnostic Ultrasound Induced Inertial Cavitation To Non-Invasively Restore Coronary And Microvascular Flow In Acute Myocardial Infarction [PDF]

, 2013
Ultrasound induced cavitation has been explored as a method of dissolving intravascular and microvascular thrombi in acute myocardial infarction. The purpose of this study was to determine the type of cavitation required for success, and whether longer ...
Everbach, E. Carr, Feng, X., Gao, S., Liu, J., Lof, J., Porter, T. R., Powers, J., Radio, S., Shi, W., Unger, E., Vignon, F., Wu, J.   +11 more
core   +31 more sources

Contribution of Streptokinase-Domains from Groups G and A (SK2a) Streptococci in Amidolytic /Proteolytic Activities and Fibrin-Dependent Plasminogen Activation: A Domain-Exchange Study [PDF]

Iranian Biomedical Journal, 2020
Background: SK, a heterogeneous PA protein from groups A, C, and G streptococci (GAS, GCS, GGS, respectively) contains three structural domains (SKα, SKβ, and SK).
Maryam Rafipour, Malihe Keramati, Mohammad Mehdi Aslani, Arash Arashkia, Farzin Roohvand   +4 more
doaj   +1 more source

Proteolyzed Variant of IgG with Free C-Terminal Lysine as a Biomarker of Prostate Cancer

Biology, 2021
The differential diagnosis of prostate cancer is problematic due to the lack of markers with high diagnostic accuracy. We previously demonstrated the increased binding of IgG to human plasminogen (PLG) in plasma of patients with prostate cancer (PC ...
Anna Lokshin, Lyudmila M. Mikhaleva, Eugene I. Goufman, Marina N. Boltovskaya, Natalia B. Tikhonova, Irina I. Stepanova, Alexandr A. Stepanov, Natalia V. Potoldykova, Andrey Z. Vinarov, Paul Stemmer, Vasily Iakovlev   +10 more
doaj   +1 more source

Hemostasis System and Plasminogen Activity in Retrochorial Hematoma in the First Trimester of Pregnancy

Biomedicines, 2022
(1) Background: The components of the fibrinolytic system and its main component, plasminogen, play a key role in the first months of pregnancy. The effect of autoantibodies interacting with plasminogen in the formation of retrochorial hematoma is ...
Natalia B. Tikhonova, Natalya B. Kuznetsova, Andrey P. Milovanov, Eugene I. Goufman, Tatiana V. Fokina, Andrey P. Aleksankin, Valentina V. Aleksankina, Irina I. Stepanova, Alexandr A. Stepanov, Marina N. Boltovskaya, Natalia V. Nizyaeva   +10 more
doaj   +1 more source

Histone 2B Facilitates Plasminogen-Enhanced Endothelial Migration through Protease-Activated Receptor 1 (PAR1) and Protease-Activated Receptor 2 (PAR2)

Biomolecules, 2022
Plasminogen and its multiple receptors have been implicated in the responses of many different cell types. Among these receptors, histone 2B (H2B) has been shown to play a prominent role in macrophage responses.
Mitali Das, Sujay Subbayya Ithychanda, Edward F. Plow   +2 more
doaj   +1 more source

DnaK Functions as a Moonlighting Protein on the Surface of Mycoplasma hyorhinis Cells

Frontiers in Microbiology, 2022
Mycoplasma hyorhinis is a common pathogen of swine and is also associated with various human tumors. It causes systemic inflammation, typically polyserositis and polyarthritis, in some infected pigs. However, the pathogenic mechanism of M.
Yao Li, Yao Li, Jia Wang, Jia Wang, Beibei Liu, Yanfei Yu, Yanfei Yu, Yanfei Yu, Ting Yuan, Yanna Wei, Yanna Wei, Yuan Gan, Jia Shao, Jia Shao, Guoqing Shao, Guoqing Shao, Guoqing Shao, Guoqing Shao, Zhixin Feng, Zhixin Feng, Zhixin Feng, Zhigang Tu, Qiyan Xiong, Qiyan Xiong, Qiyan Xiong, Qiyan Xiong   +25 more
doaj   +1 more source

Heat-Treatments Affect Protease Activities and Peptide Profiles of Ruminants' Milk

Frontiers in Nutrition, 2021
Proteases present in milk are heat-sensitive, and their activities increase or decrease depending on the intensity of the thermal treatment applied. The thermal effects on the protease activity are well-known for bovine milk but poorly understood for ...
Juliana A. S. Leite, Carlos A. Montoya, Carlos A. Montoya, Simon M. Loveday, Simon M. Loveday, Evelyne Maes, Jane A. Mullaney, Jane A. Mullaney, Jane A. Mullaney, Warren C. McNabb, Warren C. McNabb, Nicole C. Roy, Nicole C. Roy, Nicole C. Roy, Nicole C. Roy   +14 more
doaj   +1 more source

Plasminogen-Loaded Fibrin Scaffold as Drug Delivery System for Wound Healing Applications

Pharmaceutics, 2022
Plasminogen is a protein involved in intravascular and extravascular fibrinolysis, as well as in wound healing, cell migration, tissue formation and angiogenesis.
Tamer Al Kayal, Marianna Buscemi, Aida Cavallo, Ilenia Foffa, Giorgio Soldani, Paola Losi   +5 more
doaj   +1 more source

Biopharmaceutical Assessment of Mesh Aerosolised Plasminogen, a Step towards ARDS Treatment

Pharmaceutics, 2023
Acute respiratory distress syndrome (ARDS) is a severe complication of lung injuries, commonly associated with bacterial, fungal and viral infections, including SARS-CoV-2 viral infections.
Lucia Vizzoni, Chiara Migone, Brunella Grassiri, Ylenia Zambito, Baldassare Ferro, Paolo Roncucci, Filippo Mori, Alfonso Salvatore, Ester Ascione, Roberto Crea, Semih Esin, Giovanna Batoni, Anna Maria Piras   +12 more
doaj   +1 more source

The C-Terminal Domain of Staphylococcus aureus Zinc Transport Protein AdcA Binds Plasminogen and Factor H In Vitro

Pathogens, 2022
Bacterial acquisition of metals from a host is an essential attribute to facilitate survival and colonization within an infected organism. Staphylococcus aureus, a bacterial pathogen of medical importance, has evolved its strategies to acquire multiple ...
Natália Salazar, Bruno Bernardi Yamamoto, Matilde Costa Lima de Souza, Ludmila Bezerra da Silva, Ana Paula Mattos Arêas, Angela Silva Barbosa   +5 more
doaj   +1 more source