Results 101 to 110 of about 105,823 (139)

Serum Biomarkers in Atlantic Salmon for Differential Diagnosis of Cardiomyopathy Syndrome and Pancreas Disease: Proteomic Identification of Serum Fibrinogen to Enhance Troponin Immunoassay as Optimal Diagnostic Approach

Journal of Fish Diseases, EarlyView.
ABSTRACT Cardiac viral diseases are among the major causes of economic losses in Atlantic salmon (Salmo salar L.) aquaculture. These include cardiomyopathy syndrome (CMS) caused by piscine myocarditis virus (PMCV) and pancreas disease (PD) caused by Atlantic salmonid alphavirus (SAV).
Francesca Riva, Lauren Elaine Black, Kim D. Thompson, Philippe Sourd, Andrei Bordeianu, Christopher C. Chadwick, Hooman Moghadam, Jorge Del‐Pozo, Janina Costa, Richard Burchmore, Nicola Brady, Lewis Moore, Suzanne McGill, Mark McLaughlin, Peter David Eckersall   +14 more
wiley   +1 more source

Salivary Proteomics for Detecting Novel Biomarkers of Periodontitis: A Systematic Review

Journal of Periodontal Research, EarlyView.
Untargeted salivary proteomics identified promising biological molecules consistently over‐ or under‐expressed in periodontitis patients compared to periodontally healthy subjects, but further targeted approaches are required for their validation. ABSTRACT Aim Salivary content is regarded as a powerful diagnostic window for oral and systemic diseases ...
Matteo Corana, Giacomo Baima, Giovanni Iaderosa, Francesco Franco, Jianjian Zhang, Giovanni Nicolao Berta, Federica Romano, Mario Aimetti   +7 more
wiley   +1 more source

Coagulation status of immune‐mediated polyarthritis in dogs

Journal of Small Animal Practice, EarlyView.
Objective To describe the coagulation status of dogs with immune‐mediated polyarthritis. Materials and Methods Hospital records at a single referral centre were retrospectively reviewed for dogs diagnosed with immune‐mediated polyarthritis. Cases were classified as hypercoagulable, normocoagulable, hypocoagulable, or hypercoagulable and hypocoagulable ...
L. A. F. Packham, V. Black
wiley   +1 more source

Localising enzymes to biomolecular condensates increases their accumulation and benefits engineered metabolic pathway performance in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
Summary The establishment of Nicotiana benthamiana as a robust biofactory is complicated by issues such as product toxicity and proteolytic degradation of target proteins/introduced enzymes. Here we investigate whether biomolecular condensates can be used to address these problems. We engineered biomolecular condensates in N.
Anya L. Lindström Battle, Angus W. Barrett, Mark D. Fricker, Lee J. Sweetlove   +3 more
wiley   +1 more source

Identification of potential cell surface targets in patient‐derived cultures toward photoimmunotherapy of high‐grade serous ovarian cancer

Photochemistry and Photobiology, EarlyView.
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina, Anish Raju Amara, Rafay Abu, Bryan Q. Spring   +3 more
wiley   +1 more source

Adherence to physician visits for diabetes care and cardiovascular disease risk: A retrospective cohort study using an administrative claims database

Diabetes, Obesity and Metabolism, EarlyView.
Akira Okada, Yusuke Otsuka, Reiko Inoue, Yohei Hashimoto, Kayo Ikeda Kurakawa, Hideo Yasunaga, Masaomi Nangaku, Toshimasa Yamauchi, Satoko Yamaguchi, Takashi Kadowaki   +9 more
wiley   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

Etiology, pathogenesis and treatment of peri‐implantitis: A European perspective

Periodontology 2000, EarlyView.
Abstract Peri‐implantitis is a plaque‐associated pathological condition occurring in tissues around dental implants. It is characterized by inflammation in the peri‐implant mucosa and progressive loss of supporting bone. Over the last 30 years, peri‐implantitis has become a major disease burden in dentistry.
Tord Berglundh, Andrea Mombelli, Frank Schwarz, Jan Derks   +3 more
wiley   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Clot formation and resolution properties of platelets during cold storage for 21 days

Transfusion, EarlyView.
Abstract Background Cold storage (2–6°C) preserves the aggregatory and clot formation properties of platelets beyond the standard 7‐day shelf life. Comparatively little is known about the effect of cold storage on clot resolution functions, which are necessary to ensure normal hemostatic balance is maintained.
Janhavi Mahajan, Matthew P. Padula, Denese C. Marks, Lacey Johnson   +3 more
wiley   +1 more source