Results 11 to 20 of about 241,553 (351)
Clinical Chemistry, 1968 Abstract An indirect caseinolytic assay for plasminogen utilizing acid-treated plasma or serum and optimal concentrations of streptokinase is described. A linear response to increasing plasma or serum concentrations was observed. An acid-treated plasma or serum sample is preferable to euglobulin.
William R. Swaim
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Phosphorylation of human plasminogen activators and plasminogen [PDF]
FEBS Letters, 1995 Plasminogen (PG), urokinase‐type plasminogen activator (u‐PA) and tissue‐type PA (t‐PA) are the main molecules involved in fibrinolysis and in many other physiological and pathological processes. In the present study we report that human t‐PA, purified from human melanoma cells, and PG, purified from human plasma, both contain P‐Tyr residues, as ...
BARLATI, Sergio +4 more
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Haemophilia, 2008 Summary. Plasminogen deficiency has emerged as a well‐recognized disorder in which reduced levels of plasminogen lead to the development of pseudo membranes on mucosal surfaces, with subsequent end‐organ damage of the affected tissue. Ligneous conjunctivitis is the most recognizable, well‐documented, and common presentation of the clinical syndromes ...
R. Mehta, A. D. Shapiro
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Interaction of plasminogen and fibrin in plasminogen activation. [PDF]
Journal of Biological Chemistry, 1990 Glu1-, Lys77-, miniplasminogens, kringle 1-3, kringle 1-5A, and kringle 1-5R were able to bind with fibrin, while microplasminogen and kringle 4 did not bind significantly. Kringle 1-5A, but not kringle 1-3, effectively inhibited the binding of Glu1-, Lys77-, and miniplasminogens with fibrin.
Bi-Ing Chang +6 more
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Plasminogen Receptors and Fibrinolysis [PDF]
International Journal of Molecular Sciences, 2021 The ability of cells to promote plasminogen activation on their surfaces is now well recognized, and several distinct cell surface proteins have been demonstrated to function as plasminogen receptors. Here, we review studies demonstrating that plasminogen bound to cells, in addition to plasminogen directly bound to fibrin, plays a major role in ...
Lindsey A. Miles +5 more
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Identification of the binding site for plasminogen kringle 5 in the α-chain of fibrin(ogen) D-fragment [PDF]
The Ukrainian Biochemical Journal, 2020 The interaction of the fifth kringle of Glu-plasminogen with fibrin triggers activation and initiation of fibrinolysis, yet the site on fibrin that binds kringle 5 remains unknown.
L. G. Kapustianenko +4 more
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Frontiers in Cardiovascular Medicine, 2021 Chronic diseases in growing children, such as autoimmune disorders, obesity, and cancer, are hallmarked by musculoskeletal growth disturbances and osteoporosis.
Heather A. Cole +22 more
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The Pneumococcal Protein SufC Binds to Host Plasminogen and Promotes Its Conversion into Plasmin
Microorganisms, 2023 Streptococcus pneumoniae causes otitis media, sinusitis, and serious diseases such as pneumonia and bacteremia. However, the in vivo dynamics of S. pneumoniae infections and disease severity are not fully understood.
Yoshihito Yasui +7 more
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Biomedicines, 2022 Severe eosinophilic asthma is characterized by chronic airway inflammation, oxidative stress, and elevated proinflammatory cytokines, especially IL-5.
Lorenza Vantaggiato +12 more
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Synthesis of human plasminogen by the liver [PDF]
, 1980 Genetic types of plasminogen were determined from a donor and a recipient before and after hepatic homotransplantation. Examination of the plasminogen types demonstrated that the liver is the principal site of synthesis of human plasminogen.
Alper, CA +5 more
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