Results 41 to 50 of about 201,835 (360)

Mycoplasma synoviae LP78 is a fibronectin/plasminogen binding protein, putative adhesion, and potential diagnostic antigen

open access: yesFrontiers in Microbiology
Mycoplasma synoviae (M. synoviae) is one of the major poultry pathogens causing infectious synovitis, airsacculitis, a high incidence of shell breakage, and egg production loss. However, the pathogenesis of M. synoviae remains unclear.
Shuizhong Han   +8 more
doaj   +1 more source

The C-Terminal Domain of Staphylococcus aureus Zinc Transport Protein AdcA Binds Plasminogen and Factor H In Vitro

open access: yesPathogens, 2022
Bacterial acquisition of metals from a host is an essential attribute to facilitate survival and colonization within an infected organism. Staphylococcus aureus, a bacterial pathogen of medical importance, has evolved its strategies to acquire multiple ...
Natália Salazar   +5 more
doaj   +1 more source

Heat-Treatments Affect Protease Activities and Peptide Profiles of Ruminants' Milk

open access: yesFrontiers in Nutrition, 2021
Proteases present in milk are heat-sensitive, and their activities increase or decrease depending on the intensity of the thermal treatment applied. The thermal effects on the protease activity are well-known for bovine milk but poorly understood for ...
Juliana A. S. Leite   +14 more
doaj   +1 more source

DNA‐bound elastase of neutrophil extracellular traps degrades plasminogen, reduces plasmin formation, and decreases fibrinolysis: proof of concept in septic shock plasma

open access: yesThe FASEB Journal, 2019
Activation of platelets and neutrophils in septic shock results in the formation of microvascular clots containing an intricate scaffold of fibrin with neutrophil extracellular traps (NETs) DNA.
Dayana Barbosa da Cruz   +11 more
semanticscholar   +1 more source

In vitro influence on fibrinolysis parameters of aqueous extracts of mushrooms growing on woody plants

open access: yesРазработка и регистрация лекарственных средств
Introduction. Various compounds of mushroom extracts are of interest as a source of new active pharmaceutical substances with antithrombotic activity.Aim.
N. M. Faustova   +5 more
doaj   +1 more source

Biopharmaceutical Assessment of Mesh Aerosolised Plasminogen, a Step towards ARDS Treatment

open access: yesPharmaceutics, 2023
Acute respiratory distress syndrome (ARDS) is a severe complication of lung injuries, commonly associated with bacterial, fungal and viral infections, including SARS-CoV-2 viral infections.
Lucia Vizzoni   +12 more
doaj   +1 more source

Plasminogen activation in the musculoskeletal acute phase response: Injury, repair, and disease

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2020
The musculoskeletal system is critical for movement and the protection of organs. In addition to abrupt injuries, daily physical demands inflict minor injuries, necessitating a coordinated process of repair referred to as the acute‐phase response (APR ...
Breanne H.Y. Gibson   +4 more
doaj   +1 more source

Plasminogen-Loaded Fibrin Scaffold as Drug Delivery System for Wound Healing Applications

open access: yesPharmaceutics, 2022
Plasminogen is a protein involved in intravascular and extravascular fibrinolysis, as well as in wound healing, cell migration, tissue formation and angiogenesis.
Tamer Al Kayal   +5 more
doaj   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

S100A10, a novel biomarker in pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, 2018
Pancreatic cancer is arguably the deadliest cancer type. The efficacy of current therapies is often hindered by the inability to predict patient outcome.
Moamen Bydoun   +8 more
doaj   +1 more source

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