Results 251 to 260 of about 3,479,441 (357)

Imaging efficacy and safety of low dose intraventricular tissue plasminogen activator in aneurysmal subarachnoid hemorrhage: case series. [PDF]

Acta Neurochir (Wien)
Liu C, Wroe WW, Zeineddine HA, Dawes B, Giordano M, McCabe A, Chen CJ, McBride DW, Gusdon AM, Choi HA, Blackburn SL.   +10 more
europepmc   +1 more source

Adjunctive Thrombolytics After Successful Endovascular Reperfusion: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Annals of Neurology, Volume 98, Issue 6, Page 1299-1314, December 2025.
Objective The efficacy and safety of intra‐arterial thrombolysis (IAT) as an adjunct to endovascular thrombectomy (EVT) in large vessel occlusion strokes (LVOS) remain uncertain, with recent randomized controlled trials (RCTs) yielding conflicting results.
Mohamed F. Doheim, Mahmoud H. Mohammaden, Ammar Jumah, Qingwu Yang, Wenjie Zi, Yangmei Chen, Yamei Tang, Yajie Liu, Xiaochuan Huo, Liping Liu, Bernard Yan, Zhongrong Miao, Wei Hu, Chunrong Tao, Xinfeng Liu, Liqun Jiao, Xuesong Bai, Wenhuo Chen, Diogo C. Haussen, Thanh Nguyen, Raul G. Nogueira   +20 more
wiley   +1 more source

Transcranial Doppler ultrasound evaluation of vascular recanalization following tissue plasminogen activator intravenous thrombolysis in acute middle cerebral artery occlusion: A case report and literature review. [PDF]

SAGE Open Med Case Rep
Lv S, Liu R, Sun J, Liu H, Bian J, Ding C, Guo X.   +6 more
europepmc   +1 more source

Exploiting Subsite S1 of Trypsin-Like Serine Proteases for Selectivity:  Potent and Selective Inhibitors of Urokinase-Type Plasminogen Activator

, 2001
Richard L. Mackman, B.A. Katz, J. Guy Breitenbucher, Hon C. Hui, Erik Verner, Christine Luong, Liang Liu, Paul A. Sprengeler   +7 more
openalex   +1 more source

Deciphering Persistent D‐Dimer Elevation in Paraquat Poisoning: A Mortality Assessment Case Study

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT A 74‐year‐old woman accidentally ingested an unknown amount of paraquat without suicidal intent. Quickly presenting with dysphagia and tongue and oral mucosa burns, she sought medical care. Admitted to the intensive care unit, by the third day of hospitalization, due to the need to be evaluated for respiratory problems.
Behrooz Hashemi Domeneh, Ali Parouhan, Kimia Mohammadi, Masoumeh Amiri, Sasan Shafiei   +4 more
wiley   +1 more source

Poor long-term fellow-eye outcomes after vitrectomy with subretinal tissue plasminogen activator for AMD-related submacular hemorrhage. [PDF]

Graefes Arch Clin Exp Ophthalmol
Fried S, Vorobichik Berar O, David D, Arazi M, Klain B, Cohen GY, Fogel Levin M, Platner E, Katz G, Hostovsky A.   +9 more
europepmc   +1 more source

Iron enhances reactive oxygen species generation and initiates neutrophil extracellular traps formation on the endothelium to exacerbate stroke

Journal of Cell Communication and Signaling, Volume 19, Issue 4, December 2025.
Under hypoxic conditions, iron from red blood cells and injured tissues is taken up by endothelial cells. During reoxygenation, this iron is exported via Fpn1, promoting NETs formation by enhancing ROS production through the Fenton reaction, ultimately exacerbating cerebral injury.
Weijian Fan, Zebin Fang, Yuxiang Weng, Tianxiang Zhan, Kaiyuan Huang, Jianwei Pan, Renya Zhan   +6 more
wiley   +1 more source

Tissue plasminogen activator modified thromboelastography identifies fibrinolysis resistance in dogs with immune-mediated hemolytic anemia. [PDF]

Front Vet Sci
Goggs R, Davis S, Brooks MB.
europepmc   +1 more source

DL‐3‐n‐Butylphthalide Protects Mitochondria Against Ischemia/Hypoxia Damage via Suppressing GCN5L1‐Mediated Drp1 Acetylation in Neurons and Mouse Brains

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
This study provides a novel insight into the molecular mechanism whereby NBP protects mitochondria against ischemia/hypoxia damage, offering a promising drug for mitochondria‐targeting therapeutics for ischemic stroke. ABSTRACT Background Mitochondrial dysfunction is an initial event of the cascade reactions triggered by ischemic stroke, contributing ...
Haitao Zhang, Ning Zhang, Xiaotong Yang, Jiejie Zhang, Xiaoli Ge, Lei Wang, Shan Wang, Ya Wen   +7 more
wiley   +1 more source