Results 271 to 280 of about 3,389,488 (311)

Tirofiban Combination Therapy for Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 15, Issue 6, June 2025.
ABSTRACT Introduction Acute ischemic stroke (AIS) is a leading cause of morbidity and mortality globally. Standard antiplatelet therapies, while partially effective, do not fully inhibit all pathways of platelet aggregation, leaving patients at risk of recurrent thrombotic events. Tirofiban, a glycoprotein IIb/IIIa receptor inhibitor, has shown promise
Abdullah Bin Kamran, Ahmed Bazil Bin Khalil, Ayesha Muhammad, Hira Arshad, Fatima Nazir, Muhammad Mateen Ali, M. Mairaj Umar, Muhammad Farhan, Sudhair Alam, Javed Iqbal   +9 more
wiley   +1 more source

Genetic Associations of Plasminogen Activator Inhibitor-1-Related miRNA Variants with Coronary Artery Disease. [PDF]

Int J Mol Sci
Ha YH, Sung JH, Ryu CS, Ko EJ, Park HW, Park HS, Kim OJ, Kim IJ, Kim NK.   +8 more
europepmc   +1 more source

The Relationship Between Body Mass Index and Recurrence Risk of Stroke: A Systematic Review and Dose–Response Meta‑Analysis

Brain and Behavior, Volume 15, Issue 6, June 2025.
The obesity paradox can be extended to stroke recurrence. A 2% reduction in recurrence risk of stroke per 1‐unit increase in BMI. ABSTRACT Objective To explore the relationship between body mass index (BMI) and the recurrence risk of stroke. Methods We searched databases, including the Web of Science, Cochrane Library, Embase, PubMed, Chinese ...
Qiuxia Qian, Yuting Zhao, Xin Fan, Jialu Li, Jianxun Cao, Mengyu Yang, Longchun Hua, Xingxia Zhang, Ailing Yang, Fengwa Zhang, Yuxia Ma   +10 more
wiley   +1 more source

Massive Acute Thrombosis of a Mechanical Mitral Valve in a Young Patient on Acenocoumarin: A Case Report Comparing Surgical and Thrombolytic Approaches

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Obstructive mechanical mitral valve thrombosis is a life‐threatening emergency requiring urgent intervention. Surgery is often first‐line; thrombolysis may be considered in high‐risk cases. A multidisciplinary approach is essential to balance thromboembolic and bleeding risks, emphasizing early recognition, optimized anticoagulation, and ...
Said Khallikane, Bassam Bencharfa, Noureddine Atmani, Abdessamad Abdou, Ayoub Belhadj, Younes Aissaoui   +5 more
wiley   +1 more source

A meta-analysis on racial disparity in administration of tissue plasminogen activator (tPA) in stroke patients. [PDF]

Health Sci Rep
Larik MO, Bhattarai P.
europepmc   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, Volume 11, Issue 2, Page 89-104, June 2025.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

Plasminogen activator inhibitor-1 mediates cerebral ischemia-induced astrocytic reactivity. [PDF]

J Cereb Blood Flow Metab
Yanev P, Martin-Jimenez C, Vesga-Jimenez DJ, Zvinys L, Weinrich N, Cree MA, Preuss TM, Zhang X, Yepes M.   +8 more
europepmc   +1 more source

C1 inhibitor deficient hereditary angioedema is related to endothelial dysfunction in young adult and middle‐aged patients

Clinical and Translational Allergy, Volume 15, Issue 6, June 2025.
Abstract Background Hereditary angioedema (HAE) is a rare, autosomal dominantly inherited disease characterised by mucocutaneous oedema attacks. Vasoactive mediators and the endothelium play an important role in the pathogenesis of HAE. We aimed to evaluate the endothelial dysfunction in HAE. Methods The study included 35 C1 inhibitor deficient (C1‐INH)
Gokce Gul Atay Sensoy, Derya Baykız, İlkim Deniz Toprak, Deniz Eyice Karabacak, Erdem Bektas, Derya Unal, Aslı Gelincik, Semra Demir   +7 more
wiley   +1 more source

Correlation between subretinal tissue plasminogen activator and air injection rates with pressure in a retina mimicking model. [PDF]

Sci Rep
Kim NH, Lee M, Chung H, Kim HC, Lee H.
europepmc   +1 more source

The Effect of Postoperative Antithrombin Supplementation on the Inflammatory and Coagulation Status of a Surgically Treated Patient With a Malignant Tumor in the Small Pelvis—Case Series

Cancer Reports, Volume 8, Issue 6, June 2025.
ABSTRACT Introduction Antithrombin has the function of a natural anticoagulant. It is the main component of the inhibitory anticoagulant system, which, under physiological conditions, opposes the procoagulant mechanisms of hemostasis, preventing the occurrence of a hypercoagulable state, the development of thrombosis, and thromboembolic complications ...
Ranko Lazović, Ognjenka Šarenac
wiley   +1 more source