Results 271 to 280 of about 3,389,488 (311)
Tirofiban Combination Therapy for Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis
ABSTRACT Introduction Acute ischemic stroke (AIS) is a leading cause of morbidity and mortality globally. Standard antiplatelet therapies, while partially effective, do not fully inhibit all pathways of platelet aggregation, leaving patients at risk of recurrent thrombotic events. Tirofiban, a glycoprotein IIb/IIIa receptor inhibitor, has shown promise
Abdullah Bin Kamran+9 more
wiley +1 more source
Genetic Associations of Plasminogen Activator Inhibitor-1-Related miRNA Variants with Coronary Artery Disease. [PDF]
Ha YH+8 more
europepmc +1 more source
The obesity paradox can be extended to stroke recurrence. A 2% reduction in recurrence risk of stroke per 1‐unit increase in BMI. ABSTRACT Objective To explore the relationship between body mass index (BMI) and the recurrence risk of stroke. Methods We searched databases, including the Web of Science, Cochrane Library, Embase, PubMed, Chinese ...
Qiuxia Qian+10 more
wiley +1 more source
ABSTRACT Obstructive mechanical mitral valve thrombosis is a life‐threatening emergency requiring urgent intervention. Surgery is often first‐line; thrombolysis may be considered in high‐risk cases. A multidisciplinary approach is essential to balance thromboembolic and bleeding risks, emphasizing early recognition, optimized anticoagulation, and ...
Said Khallikane+5 more
wiley +1 more source
A meta-analysis on racial disparity in administration of tissue plasminogen activator (tPA) in stroke patients. [PDF]
Larik MO, Bhattarai P.
europepmc +1 more source
Contemporary Perspectives on Chronic Renal Disorders
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok+5 more
wiley +1 more source
Plasminogen activator inhibitor-1 mediates cerebral ischemia-induced astrocytic reactivity. [PDF]
Yanev P+8 more
europepmc +1 more source
Abstract Background Hereditary angioedema (HAE) is a rare, autosomal dominantly inherited disease characterised by mucocutaneous oedema attacks. Vasoactive mediators and the endothelium play an important role in the pathogenesis of HAE. We aimed to evaluate the endothelial dysfunction in HAE. Methods The study included 35 C1 inhibitor deficient (C1‐INH)
Gokce Gul Atay Sensoy+7 more
wiley +1 more source
Correlation between subretinal tissue plasminogen activator and air injection rates with pressure in a retina mimicking model. [PDF]
Kim NH, Lee M, Chung H, Kim HC, Lee H.
europepmc +1 more source
ABSTRACT Introduction Antithrombin has the function of a natural anticoagulant. It is the main component of the inhibitory anticoagulant system, which, under physiological conditions, opposes the procoagulant mechanisms of hemostasis, preventing the occurrence of a hypercoagulable state, the development of thrombosis, and thromboembolic complications ...
Ranko Lazović, Ognjenka Šarenac
wiley +1 more source