Objectives The primary objective of this study was to evaluate viscoelastic profiles in heartworm antigen‐positive versus antigen‐negative dogs using a point‐of‐care viscoelastic device. A secondary objective was to compare intraoperative bleeding and surgical duration between these same groups.
B. K. Newmans+4 more
wiley +1 more source
Cooperative Binding of Smad Proteins to Two Adjacent DNA Elements in the Plasminogen Activator Inhibitor-1 Promoter Mediates Transforming Growth Factor β-induced Smad-dependent Transcriptional Activation [PDF]
Shannon L. Stroschein+2 more
openalex +1 more source
Coagulation status of immune‐mediated polyarthritis in dogs
Objective To describe the coagulation status of dogs with immune‐mediated polyarthritis. Materials and Methods Hospital records at a single referral centre were retrospectively reviewed for dogs diagnosed with immune‐mediated polyarthritis. Cases were classified as hypercoagulable, normocoagulable, hypocoagulable, or hypercoagulable and hypocoagulable ...
L. A. F. Packham, V. Black
wiley +1 more source
Natriuretic Factors and Nitric Oxide Suppress Plasminogen Activator Inhibitor-1 Expression in Vascular Smooth Muscle Cells [PDF]
Julie L. Bouchie+2 more
openalex +1 more source
Receiver operating characteristic curves to assess the ability of preoperative levels of inflammatory markers to predict acute infection within 90 days after total joint arthroplasty in patients with rheumatoid arthritis. (A) C‐reactive protein (CRP), erythrocyte sedimentation rate (ESR), or plasma fibrinogen (FIB). (B) Neutrophil‐lymphocyte ratio (NLR)
Yahao Lai+6 more
wiley +1 more source
Gene Polymorphisms for Plasminogen Activator Inhibitor-1/Tissue Plasminogen Activator and Development of Allograft Coronary Artery Disease [PDF]
Raymond L. Benza+8 more
openalex +1 more source
Summary The establishment of Nicotiana benthamiana as a robust biofactory is complicated by issues such as product toxicity and proteolytic degradation of target proteins/introduced enzymes. Here we investigate whether biomolecular condensates can be used to address these problems. We engineered biomolecular condensates in N.
Anya L. Lindström Battle+3 more
wiley +1 more source
Identification of a cis-Acting Sequence in the Human Plasminogen Activator Inhibitor Type-1 Gene That Mediates Transforming Growth Factor-β1 Responsiveness in Endothelium in Vivo [PDF]
Gang Dong+3 more
openalex +1 more source
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina+3 more
wiley +1 more source
Conformational Changes of the Reactive‐Centre Loop and β‐Strand 5A Accompany Temperature‐Dependent Inhibitor‐Substrate Transition of Plasminogen‐Activator Inhibitor 1 [PDF]
Lars Kjøller+5 more
openalex +1 more source