Results 231 to 240 of about 112,049 (293)

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, Volume 183, Issue 9, Page 1747-1778, May 2026.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

Comment on "Role of increased plasminogen activator inhibitor-1 and vitronectin in gestational diabetes mellitus". [PDF]

Rev Assoc Med Bras (1992)
Yin H, Shi R.
europepmc   +1 more source

Modulation of the gut microbiota as a novel strategy to prevent anastomotic leak after colorectal surgery: Systematic scoping review

Colorectal Disease, Volume 28, Issue 5, May 2026.
Abstract Background Anastomotic leak (AL) remains a major source of morbidity following colorectal surgery. Increasing evidence implicates the gut microbiome in the pathogenesis of AL, with certain microbial species disrupting tissue repair through collagen degradation.
Jack A. Helliwell, Peter Sciberras, Alexios Dosis, Joshua Burke, Caroline H. Chilton, Henry M. Wood, David G. Jayne   +6 more
wiley   +1 more source

Insights Into Remote Ischemic Conditioning miRNA Effects on Brain Endothelial Cells During Ischemia–Reperfusion

Microcirculation, Volume 33, Issue 4, May 2026.
ABSTRACT Objective Acute ischemic stroke (AIS) is one of the leading causes of death and disabilities, and as such, it is of utmost importance to identify novel treatment options. Remote ischemic conditioning (RIC) is a promising non‐invasive treatment that is thought to activate the body's own protective mechanisms against damaging ischemia.
Katrine Tang Stenz, Jesper Just, Zenghui Huang, Thomas Ravn Lassen, Kristian Vissing, Xiu‐Jie Wang, Kim Ryun Drasbek   +6 more
wiley   +1 more source

Peptide Angio‐3 Attenuates Pulmonary Fibrosis Via Modulation of the Coagulation Factor Xa—Protease‐Activated Receptor‐1 Signaling Axis

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Schematic illustrating the mechanism by which the peptide Angio‐3 attenuates pulmonary fibrosis. Following lung injury, activation of the coagulation cascade via Factor Xa (FXa) signals through protease‐activated receptor‐1 (PAR‐1) to activate fibroblasts and promote fibrosis.
Dan Wang, Fei Li, Hui Chen, Bochuan Deng, Lu Cheng, Jiawen Ma, Rong Li, Lang Qu, Junqiu Xie, Ya Zhao   +9 more
wiley   +1 more source

Effects of resveratrol supplementation on serum concentrations of plasminogen activator inhibitor-1, fibroblast growth factor 21, and adiponectin in patients with nonalcoholic fatty liver disease. [PDF]

BMC Nutr
Farzin L, Mansouri E, Salehi S, Baker E, Amirkhizi F, Asghari S.   +5 more
europepmc   +1 more source

Effects of plasminogen activator inhibitor-1 deficiency on bone disorders and sarcopenia caused by adenine-induced renal dysfunction in mice. [PDF]

PLoS One
Mizukami Y, Kawao N, Ohira T, Okada K, Yamao H, Matsuo O, Kaji H.   +6 more
europepmc   +1 more source

plasminogen activator inhibitor-1 (PAI-1)

Journal of JCS Cardiologists, 2005
openaire   +2 more sources

The influence of 4G/5G polymorphism in the plasminogen-activator-inhibitor-1 promoter on COVID-19 severity and endothelial dysfunction. [PDF]

Front Immunol
Yatsenko T, Rios R, Nogueira T, Salama Y, Takahashi S, Adachi E, Tabe Y, Hattori N, Osada T, Naito T, Takahashi K, Hattori K, Heissig B.   +12 more
europepmc   +1 more source

A signaling pathway map of plasminogen activator inhibitor-1 (PAI-1/SERPINE-1): a review of an innovative frontier in molecular aging and cellular senescence. [PDF]

Cell Commun Signal
Shaikh SB, Balaya RDA, Dagamajalu S, Bhandary YP, Unwalla H, Prasad TSK, Rahman I.   +6 more
europepmc   +1 more source