Results 241 to 250 of about 108,172,160 (276)
Some of the next articles are maybe not open access.
Urokinase-type plasminogen activator and its inhibitor plasminogen activator inhibitor-1
Oncology Reports, 1997Tumor associated proteolysis is an essential mechanism in invasion and metastasis of cancer. The influence of the serine protease urokinase-like plasminogen activator (u-PA) and its inhibitor plasminogen activator inhibitor-1 (PAI-1) on the clinical prognosis of squamous carcinoma of the head and neck region (HNSCC) was evaluated. U-PA and PAI-1 levels
B, Wollenberg +4 more
openaire +2 more sources
Diabetes, 1995
Plasminogen activator inhibitor 1 (PAI-1) activity is increased in patients with non-insulin-dependent diabetes mellitus (NIDDM) and may contribute to their excess risk of cardiovascular disease. We examined the determinants of PAI-1 activity in 146 NIDDM subjects by using specific assays of insulin and intact and des-31,32-proinsulin and measures of ...
A, Panahloo +5 more
openaire +2 more sources
Plasminogen activator inhibitor 1 (PAI-1) activity is increased in patients with non-insulin-dependent diabetes mellitus (NIDDM) and may contribute to their excess risk of cardiovascular disease. We examined the determinants of PAI-1 activity in 146 NIDDM subjects by using specific assays of insulin and intact and des-31,32-proinsulin and measures of ...
A, Panahloo +5 more
openaire +2 more sources
Fibrinolysis, 1994
Abstract The relationship between PAI activity, active PAI-1 concentration and whole PAI-1 concentration was determined in 180 plasma samples of unselected ambulant patients of the department of internal medicine. To exclude a release of platelet PAI-1 after blood sampling, different anticoagulants and temperatures of blood storage were tested.
G. Siegert, Th. Fritz, E. Runge
openaire +1 more source
Abstract The relationship between PAI activity, active PAI-1 concentration and whole PAI-1 concentration was determined in 180 plasma samples of unselected ambulant patients of the department of internal medicine. To exclude a release of platelet PAI-1 after blood sampling, different anticoagulants and temperatures of blood storage were tested.
G. Siegert, Th. Fritz, E. Runge
openaire +1 more source
Solvent Effects on Activity and Conformation of Plasminogen Activator Inhibitor-1
Thrombosis and Haemostasis, 1999SummaryWe have studied effects of the solvent composition on the activity and the conformation of human plasminogen activator inhibitor-1 (PAI-1) from HT-1080 fibrosarcoma cells. Non-ionic detergents, including Triton X-100, reduced the inhibitory activity of PAI-1 more than 20-fold at 0° C, but less than 2-fold at 37° C, while glycerol partly ...
Andreasen, Peter +3 more
openaire +3 more sources
Plasminogen Activator Inhibitor 1 and Atherothrombosis
Thrombosis and Haemostasis, 1993I, Juhan-Vague, M C, Alessi
openaire +2 more sources
Vascular Regulation of Plasminogen Activator Inhibitor-1 Activity
Seminars in Thrombosis and Hemostasis, 1994J M, Edelberg, D C, Sane, S V, Pizzo
openaire +2 more sources