Results 21 to 30 of about 59,929 (255)
Frontiers in Cellular and Infection Microbiology, 2023 Severe acute respiratory syndrome coronavirus-2 causes hyperinflammation and activation of coagulation cascade and, as a result, aggravates endothelial cell dysfunction. N-acetylcysteine and Sulodexide have been found to mitigate endothelial damage.
Justyna Rajewska-Tabor +5 more
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Tissue plasminogen activator and plasminogen activator inhibitor 1 contribute to sonic hedgehog-induced in vitro cerebral angiogenesis. [PDF]
PLoS ONE, 2012 The molecular mechanisms underlying cerebral angiogenesis have not been fully investigated. Using primary mouse brain endothelial cells (MBECs) and a capillary-like tube formation assay, we investigated whether the sonic hedgehog (Shh) signaling pathway ...
Hua Teng +6 more
doaj +1 more source
Clinics, 2012 OBJECTIVE: The development of osteoporosis is associated with several risk factors, such as genetic structures that affect bone turnover and bone mass. The impact of genetic structures on osteoporosis is not known.
Merih Ozgen +8 more
doaj +1 more source
The pharmacokinetics of plasminogen activator inhibitor-1 in the rabbit [PDF]
Blood, 1990 Abstract The pharmacokinetics of the activated and latent forms of plasminogen activator inhibitor-1 (PAI–1) isolated from HT1080 fibrosarcoma cells (HT1080 PAI-1) and a nonglycosylated form of human PAI-1 isolated from a yeast expression system (rPAI-1) were followed in the rabbit.
E J, Mayer +4 more
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Plasminogen influence on the PAI-1 release by human platelets [PDF]
The Ukrainian Biochemical JournalРАІ-1 (plasminogen activator inhibitor type 1), as a major physiological inhibitor of tissue plasminogen activator and urokinase, plays a key role in the regulation of fibrinolysis in vivo.
O. I. Yusova +3 more
doaj +1 more source
Plasminogen activator inhibitor 1 and gestational diabetes: the causal relationship
Diabetology & Metabolic Syndrome, 2022 Plasminogen activator inhibitor 1 (PAI-1) also known as serpin E1 or endothelial plasminogen activator inhibitor, is produced from endothelial cells and adipose tissue.
Gaber El-Saber Batiha +6 more
doaj +1 more source
Folia Histochemica et Cytobiologica, 2008 Urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) have been associated with asthma. The aim of this study was to evaluate concentration of uPA and PAI-1 in induced sputum of house dust mite allergic asthmatics (HDM-AAs).
Sebastian Zukowski +3 more
doaj +1 more source
Plasminogen activator inhibitor-1 (PAI-1) expression in endometriosis.
PLoS ONE, 2019 PurposeDeep infiltrating endometriosis (DIE) is defined as an endometriotic lesion penetrating to a depth of >5 mm and is associated with pelvic pain, but the underlying mechanisms are unclear.
Fahad T Alotaibi +8 more
doaj +1 more source
Egyptian Journal of Medical Human Genetics, 2018 Background: Many genetic factors, including polymorphisms in the genes regulating blood coagulation and fibrinolysis have been proposed as risk factors for coronary artery disease (CAD).
Hanan Al-Wakeel +3 more
doaj +1 more source
Plasminogen Activator Inhibitor-1 [PDF]
Circulation, 2013 Hypertension is the most common reversible risk factor for stroke, myocardial infarction, and heart failure, affecting >60 million individuals in the United State alone and 1 billion globally.1 According to the World Health Organization, hypertension is now the leading cause of preventable death worldwide.2 Importantly, the prevalence and complications
Daniel I, Simon, Norman M, Simon
openaire +2 more sources