Results 31 to 40 of about 180,408 (257)
Translocation of plasminogen activator inhibitor-1 during serum stimulated growth of mouse embryo fibroblasts [PDF]
, 1990 Serum-stimulated mouse embryo fibroblasts specifically secrete two proteins of molecular weights 48,000 and 26,000. The 48 kDa protein showed affinity to concanavalin A and was precipitated by antibody to plasminogen activator inhibitor ...
Nagashunmugam, T. +2 more
core +1 more source
Journal of Clinical Apheresis, Volume 37, Issue 6, Page 534-543, December 2022., 2022 Abstract Introduction Therapeutic plasma exchange (TPE) is used for several chronic conditions with little evidence on the efficacy and safety of different choice of replacement fluid. Measurement of haemostasis, particularly in vitro thrombin generation, could play a role in determining the immediate efficacy of different fluid replacement.
Ruchika Kohli +6 more
wiley +1 more source
Plasminogen influence on the PAI-1 release by human platelets [PDF]
The Ukrainian Biochemical JournalРАІ-1 (plasminogen activator inhibitor type 1), as a major physiological inhibitor of tissue plasminogen activator and urokinase, plays a key role in the regulation of fibrinolysis in vivo.
O. I. Yusova +3 more
doaj +1 more source
Role of plasminogen activator inhibitor-1 (PAI-1) in cancer stem cells [PDF]
World Cancer Research Journal, 2022 Objective: Plasminogen Activator Inhibitor-1 has an important role in the progression of cancer. Although there are many studies about the relation of Plasminogen Activator Inhibitor-1 (PAI-1) with cancer, there exists only a few about showing the ...
M. Irmak-Yazicioglu, K. Ergun
doaj +1 more source
The Journal of Clinical Pharmacology, Volume 63, Issue 2, Page 197-209, February 2023., 2023 Abstract The pharmacokinetics (PK) of tenecteplase in patients with acute ischemic stroke has not been extensively studied. This study aimed to describe PK characteristics of tenecteplase in patients with acute myocardial infarction (AMI) using a population PK approach and to assess applicability of the findings to patients with acute ischemic stroke ...
Fei Tang +7 more
wiley +1 more source
Folia Histochemica et Cytobiologica, 2008 Urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) have been associated with asthma. The aim of this study was to evaluate concentration of uPA and PAI-1 in induced sputum of house dust mite allergic asthmatics (HDM-AAs).
Sebastian Zukowski +3 more
doaj +1 more source
The uPA System Differentially Alters Fibroblast Fate and Profibrotic Ability in Skin Fibrosis
Frontiers in Immunology, 2022 Skin fibrosis is a common pathological feature of various diseases, and few treatment strategies are available because of the molecular pathogenesis is poorly understood.
Ming-Li Zou +15 more
doaj +1 more source
Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome [PDF]
, 2018 We analyzed the levels of circulating tissue plasminogen activator (tPA) and plasminogen activator inhibitor (PAI)-1 in acute hantavirus cardiopulmonary syndrome (HCPS) and hemorrhagic fever with renal syndrome (HFRS).
Avsic-Zupanc, Tatjana +8 more
core +2 more sources
Active chiral molecules in activity gradients [PDF]
, 2022 While the behavior of active colloidal molecules is well studied by now for a constant activity, the effect of activity gradients is much less understood. Here we explore one of the simplest molecules in activity gradients, namely active chiral dimers composed of two particles with opposite active torques of the same magnitude.
arxiv +1 more source
Plasminogen Activator Inhibitor-1 Promotes Neutrophil Infiltration and Tissue Injury on Ischemia–Reperfusion [PDF]
, 2018 Objective Ischemia-reperfusion (I/R) injury significantly contributes to organ dysfunction and failure after myocardial infarction, stroke, and transplantation.
Fabritius, Matthias +15 more
core +1 more source