Kinetic analysis of the interaction between plasminogen activator inhibitor-1 and tissue-type plasminogen activator [PDF]
Christine Masson, Eduardo Anglés‐Cano
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(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez+5 more
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A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
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Purification of active human plasminogen activator inhibitor 1 from Escherichia coli [PDF]
Daniel A. Lawrence+3 more
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In mouse diet‐induced obesity models, the brain penetrant NLRP3 inhibitor NT‐0796 enhances and sustains the efficacy of the GLP‐1RA semaglutide, leading to a complete reversal of obesity. This correlates with reduced peripheral inflammation and anti‐neuroinflammatory activities, including a reduction in hypothalamic gliosis suggesting further benefits ...
Peter Thornton+6 more
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RFLP for Sst I (Sac I) at the human plasminogen activator inhibitor type 1 (PAI-1) gene locus [PDF]
Ikuko Kondo, K. Berg
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Abstract Objective Evaluate the use of tranexamic acid (TXA) and observation as a management option for pediatric patients presenting with posttonsillectomy hemorrhage (PTH). Study Design Retrospective analysis of a prospectively implemented quality improvement initiative with a historical control comparison group. Setting Tertiary children's hospital.
Laura A. Petrauskas+12 more
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A comparison between activated protein C and des-1-41-light chain- activated protein C in reactions with type 1 plasminogen activator inhibitor [PDF]
CL Gladson+4 more
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Progress in Aptamer Research and Future Applications
This paper mainly describes the screening method of aptamer, the screening difficulties and improvement methods of small molecule aptamer, and the application and treatment of aptamer. It explores the latest progress and application of aptamers, and summarises them, thus indicating some problems that still exist in this field.
Song Liu+4 more
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Mechanism of glucocorticoid induction of the rat plasminogen activator inhibitor-1 gene in HTC rat hepatoma cells: identification of cis-acting regulatory elements. [PDF]
C.J. Bruzdzinski+4 more
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