Results 211 to 220 of about 91,776 (288)

Rhenium‐Based β‐Galactosidase Probe Allows Senescence Profiling by Mass Cytometry

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
Senescence‐associated β‐galactosidase (SA‐β‐Gal) activity is a widely accepted biomarker of cellular senescence, yet its integration with other senescence markers has been limited by available detection methods. Here, we introduce ReGal, a mass cytometry‐compatible SA‐β‐Gal activity probe that can be multiplexed with established markers of senescence ...
Adam Tam, Kris Elbein, Aleida G. Gonzalez, Edgar A. Arriaga, Mark Nitz   +4 more
wiley   +2 more sources

Tetranectin: Molecular Mechanisms, Biological Functions and Clinical Implications. [PDF]

Int J Mol Sci
Ahmed S, Iram S, Akash A, Kim K, Kim J.
europepmc   +1 more source

From Dysbiosis to Disease: How Vaginal Microbiota Shape Group B Streptococcus Pathogenesis

ChemBioChem, Volume 27, Issue 20, 28 October 2026.
Lactobacillus crispatus plays a critical role in the vaginal microbiome. Limiting glucose shifts metabolism toward HMO consumption and amino acid metabolism. These actions enable alkali production and competition. Homeostasis, characterized by dense Lactobacilli colonization and suppression of pathogens, provides resistance to dysbiosis.
Julie A. Talbert, Steven D. Townsend
wiley   +1 more source

Plasminogen Activator Inhibitor-1 is Internalized by Endothelial Cells via A Pinocytosis-Like Mechanism and Evades Degradation. [PDF]

FASEB J
McAdow M, Ahmetaj G, Hauschel R, Eichmann A, Sessa W.   +4 more
europepmc   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

COX-2/PGE₂ signaling drives Toxocara canis-induced lung pathology by enhancing plasminogen activator activity and collagen VI degradation. [PDF]

Sci Rep
Lai SC, Lu CY, Chuang CY, Lee HH, Lee MC, Chen KM.   +5 more
europepmc   +1 more source

Toward improved thrombolysis in ischemic stroke: targeting nonfibrin components. [PDF]

Res Pract Thromb Haemost
De Meyer SF.
europepmc   +1 more source

L-(+)-Ergothioneine ameliorates preeclampsia-associated vascular endothelial dysfunction by modulating the Nrf2-PPARγ-sFlt-1 axis. [PDF]

PLoS One
Gong J, Liu Y, Meng Q, Wu J, Chen F, Xu Y, Li Y, Luo Q.   +7 more
europepmc   +1 more source

Ovarian Cyst Fluid as a Resource for Diagnostic and Prognostic Biomarker Discovery in Ovarian Lesions. [PDF]

Cancers (Basel)
Aboelnasr LS, Deol N, Fu YJ, El-Bahrawy M.   +3 more
europepmc   +1 more source

Senescent cardiac cells promote thrombus formation and impair fibrinolysis. [PDF]

Geroscience
Shahar T, Ezra N, Chen S, Kryukov O, Cohen S.   +4 more
europepmc   +1 more source