Results 281 to 290 of about 3,326,153 (390)

Assessing Causality Between Endocrine, Nutritional, and Metabolic Disease and Pulmonary Tuberculosis: A Mendelian Randomization Study

Health Science Reports, Volume 8, Issue 6, June 2025.
Abstract Background and Aims Observational studies frequently report co‐occurrence between endocrine, nutritional, and metabolic disease (ENMD) and pulmonary tuberculosis (PTB). However, the causal properties between them remain poorly defined. Our aim in this study was to investigate the causal effect of ENMD on PTB using Mendelian randomization ...
Yan Gao, Yiguo Wang, Jinwen Su, Chunxia Zhang, Qiming Zhang, Zhi Chen   +5 more
wiley   +1 more source

Mechanisms behind elevated serum levels of plasminogen activator inhibitor-1 in frontotemporal lobar degeneration. [PDF]

Neural Regen Res
Angelucci F, Hort J.
europepmc   +1 more source

Enolase and 16.5‐kDa Tegument‐Associated Protein in Fasciola hepatica Extracellular Vesicles: Clues to Their Role in Pathogenesis

Journal of Extracellular Biology, Volume 4, Issue 6, June 2025.
Recombinant enolase and 16.5 tegumentary proteins from F. hepatica EVs may influence the progression of fibrosis, altering cell growth, proteomic profiles, and EVs secretion in macrophages, hepatic stellate cells (HSCs) and hepatocytes. r‐Fhenolase reduced fibrosis markers in HSCs and exhibited anti‐inflammatory properties in macrophages, and r‐Fh16 ...
Aránzazu González‐Arce, Christian M. Sánchez‐López, Liz F. Sánchez‐Palencia, Antonio Marcilla, Dolores Bernal   +4 more
wiley   +1 more source

Unlocking Alzheimer's Disease: The Role of BDNF Signaling in Neuropathology and Treatment. [PDF]

Neuromolecular Med
Alqahtani SM, Al-Kuraishy HM, Al Gareeb AI, Albuhadily AK, Alexiou A, Papadakis M, Hemeda LR, Faheem SA, El-Saber Batiha G.   +8 more
europepmc   +1 more source

Proteomics of Urinary Extracellular Vesicles Highlight the Involvement of Vitronectin and the Fibrinolytic and TNF Pathways as Mechanisms Underlying Renal Fibrosis in Kidney Transplant Patients

Journal of Extracellular Biology, Volume 4, Issue 6, June 2025.
ABSTRACT Vitronectin (VTN) is a potential non‐invasive biomarker for renal fibrosis, originally described in urinary extracellular vesicles (uEV) from kidney transplant patients (KTx). However, VTN's specific role in renal fibrosis is unclear, as it is involved in various physiological processes.
Marta Clos‐Sansalvador, Sergio G. Garcia, Paula Rodríguez‐Martínez, Marta Sanroque‐Muñoz, Miriam Font‐Morón, Cristina Grange, Benedetta Bussolati, Marcella Franquesa, Javier Juega, Francesc E. Borràs   +9 more
wiley   +1 more source

Fucoidan alginate and sulfated alginate microbeads induce distinct coagulation, inflammatory and fibrotic responses. [PDF]

Mater Today Bio
Vasuthas K, Kjesbu JS, Brambilla A, Levitan M, Coron AE, Fonseca DM, Strand BL, Slupphaug G, Rokstad AMA.   +8 more
europepmc   +1 more source

Angioedema following venipuncture in a patient on angiotensin‐converting enzyme inhibitor and dipeptidyl peptidase‐IV inhibitor therapy: A case report

JEADV Clinical Practice, Volume 4, Issue 2, Page 510-513, June 2025.
Capsule SummaryAcquired angioedema (AAE) is a rare and potentially life‐threatening condition resulting from disruption of bradykinin (BK) metabolism, most often drug‐induced, with attacks typically triggered by major trauma. We report an uncommon case of AAE triggered locally by minor trauma—a forearm venipuncture—in a 77‐year‐old male taking ramipril
Adrien Bénic, Adrien Boyard, Alexan Pogossian, Laurent Misery, Anne‐Marie Roguedas‐Contios   +4 more
wiley   +1 more source

Exploiting the Molecular Properties of Fibrinogen to Control Bleeding Following Vascular Injury. [PDF]

Int J Mol Sci
Singh T, Hasan M, Gaule TG, Ajjan RA.
europepmc   +1 more source

Preascitic Sodium Retention in Cirrhosis: A Role for Disregulated Proteolysis by Proprotein Convertases?

Liver International Communications, Volume 6, Issue 2, June 2025.
ABSTRACT Loss of effective arterial blood volume, secondary hyperaldosteronism, adrenergic activation and nonosmotic hypersecretion of vasopressin induce sodium and water retention in cirrhotic patients with ascites. The mechanisms of sodium retention that precede ascites formation remain elusive.
Giovanni Sansoè, Manuela Aragno, Florence Wong   +2 more
wiley   +1 more source

Platelets: Novel Biomaterials for Cancer Diagnosis and Therapeutic Delivery

MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
Platelets, particularly tumor‐educated platelets (TEPs), play a crucial role in cancer diagnosis and treatment. TEPs undergo molecular changes in RNA and protein profiles, making them valuable biomarkers for diagnosis, prognosis, and monitoring. In nanomedicine, platelets serve as drug carriers in tumor‐targeted nanomaterials, enhancing specificity and
Xin Wang, Jie Chen, Hubing Shi
wiley   +1 more source